Bone Metastases Of CT, MRI Application

Purpose:By 244 patients with bone metastases of CT, MRI and new technology research, comparison of CT and MRI showed the sensitivity of bone metastases. Analysis of the primary system and in different histological types of malignant tumors of bone metastases involved sites, video perfor-mance, the situation type and soft tissue invasion. Magnetic resonance diffusion-weighted imaging of the body (WB-DWI) display of bone metas-tases.Material and Methods:Collected in our hospital since March 2008-March 2010, confirmed by pathology and clinical follow and has a primary focus of the 244 cases of patients with bone metastases.129 cases were male and female 115 cases, aged 27-88 years, mean 54.5 years old. Siemens SOMATOM Emotion 16 layer and the GE Lightspeed 16-slice spiral CT and 4-layer machine, GE Signa 1.5T MRI.Observation of CT, MRI of bone metastases show the situation, such as:location, shape, density or signal change, soft tissue mass and surrounding tissue invasion case; WB-DWI showed metastases of the vertebral;sources of different systems and tissue distribution of bone metastases. The original metastatic malignant lesions including respiratory, breast, digestive system cancer, urinary system cancer, reproductive system cancer and other malignancies. The histological types including adenocarcinoma, squamous cell carcinoma, transitional cell carcinoma, papillary carcinoma, invasive ductal carcinoma, pure carcinoma, small cell carcinoma, clear cell carcinoma and other rare malignant tumors (inflammatory carcinoma, hard carcinoma, invasive lobular carcinoma, non-small cell carcinoma, salivary duct carcinoma, lymphoma, undifferen-tiated carcinoma, malignant melanoma, endometrial cancer, malignant thymoma, malignant stromal tumor, hepatocellular carcinoma signet-ring cell carci- noma). Observations using theχ2 test, completed by the Statistical Package for SPSS 11.5 version.Results:(1) MRI showed vertebral bodies and accessories in the number of lesions than CT, byχ2 test, the difference was significant (P<0.05).(2) Different system from the tumor bone metastases in the spine and ribs, spine and limbs, ribs and limbs, chest and limbs of the distribution of the difference was not statistically significant (P>0.05). From respiratory, breast, digestive system, genitourinary system, the distribution of bone metastases were more than breast and pelvic spine, from respiratory, breast, digestive system and the distribution of bone metastases than breast and pelvic ribs, from respiratory, bone metastases of breast sternum and limbs more than the distribution of pelvis, the differences were significant (P<0.05).(3) Different histological types of malignant tumors of bone metastases in the spine and ribs, sternum and ribs, spine and limbs, ribs and limbs, chest and limbs, spine and pelvic bones, ribs and pelvic bones, limbs and pelvis bone distribution was no significant difference (P>0.05). From adenocarcinoma, squamous cell carcinoma, invasive ductal carcinoma of bone metastases in the spine of the distribution are more than the sternum, the difference was significant (P<0.05).(4) From different systems into a bone tumor due to metastasis and mixed-type metastasis was no difference in the distribution. From different systems into a malignant type of bone metastases and osteolytic type metastases, osteolytic metastases and mixed-type metastasis difference between the distribution of, into bone metastases and mixed-type metastasis main source of primary tumor in the respiratory system, breast, urogenital system, osteolytic type of primary tumor metastases mainly from the digestive system.(5) Different histological types of malignant tumors induced osteo-genic metastases and osteolytic type metastases, osteolytic metastases and mixed type metastases, osteogenic metastases and metastases in the dist-ribution of hybrid difference was not statistically significant (P>0.05). Adenocarcinoma and squamous cell carcinoma induced osteogenic metasta-ses and hybrid differences in the distribution of metastases was signi-ficantly (P<0.05). Mainly in squamous cell carcinoma metastasis of mixed higher than adenocarcinoma, adenocarcinoma type osteogenic and osteoly-tic metastasis was higher than squamous cell carcinoma.(6) From respiratory, breast, digestive system, genitourinary system, bone metastases were less than the number of surrounding soft tissue invasion is not the number of invasion, there were significant differences (P<0.05). Which originated from the genitourinary system of soft tissue around the bone and metastatic tumor invasion of the largest proportion.(7) Different histological types of malignant tumors of bone metastases in soft tissue around the invaded area is no significant difference (P>0.05).Conclusion:On 244 patients with bone metastases of image analysis found:1. In the 81 spinal bone metastases routine CT and MRI, MRI more sensitive than CT. MRI showed more the number of CT lesions, mainly in the discovery of vertebral lesions. Aspects in the application of MRI sequences, WB-DWI showed more number of lesions.2. CT and MRI imaging of bone metastases performance and position of the display will help to further evaluate the source of the primary tumor and histological type:(1) Spine and rib metastases from lung, breast, digestive system neoplasms.Spine and pelvis of tumor metastasis from the urinary and reproductive system cancer.(2) From adenocarcinoma, squamous cell carcinoma and invasive ductal carcinoma with bone metastases mainly in the spine and ribs.(3) Osteoblastic and mixed metastases, primary tumor mainly from respiratory, breast, genitourinary system. Osteolytic metastases type, primary tumor mainly from the digestive system.(4) Mixed metastases, histological type of squamous cell carcinoma compared with adenocarcinoma, made of bone metastases type and osteolytic type, histological type of adenocarcinoma compared with squa-mous cell carcinoma more.(5) Soft tissue invasion of the bone metastases, mainly from the urogenital system tumors, followed by digestive system cancer and breast cancer. (6) Soft tissue invasion of bone metastases, histological type most common in squamous cell carcinoma, followed by invasive ductal carci-noma and adenocarcinoma.