| Objective:To explore and discuss the incidence of some possible relative factors in men with androgenic alopecia(AGA), the incidence of metabolic syndrome(MS), benign prostatic hyperplasia(BPH) and its the relationship between AGA and the risk factors of metabolic syndmme(MS), cardiovascular events.Methods:Cases were 63 men with AGA on stage I-VII in the Hamilton-Norwood classification between January and March 2010 in international health cwere center of Second Affiliated Hospital Zhejiang University College of Medicine, and to select 43 men with hair loss on top of head from the cases as another group. Controls were 64 men frequency matched by age and identified by random digit dialing. To collect the age of onset, family history, psychic factor, life style, and disease history,and some other relative factors of all cases,and analyse them And evaluate the body mass index(BMI), total cholesterin, glycerinate, high density lipopmtein cholesterol(HDL-C), low density lipopmtein cholesterol(HDL-C), glucose, serum uric acid and, as well as Hepatobiliary ultrasonic, prostatic ultrasonic of all 3 groups, compwere the difference between them, analyse the incidence and aggregation of the risk factors of MS, cardiovascular events, he relativity between them, and the incidence of BPH.Results:(1) The average age of 63 men was 46.19±9.53 years old, many were 40-60 years, the age of onset of most of them were 31-40 years.34 cases(53.97%) have the family history of AGA, and most were fathers(22 casese,34.92%).20.24%cases got the big pressure.20.63% cases like greasy.36.51% cases smoke.34.92% cases like drinking.15.87% cases got hypertension,6.35% cases got diabetes,3.17% cases got coronary heart disease. The common stages in the Hamilton-Norwood classification of AGA were III vertex, (15.87%) IV(14.29%) and V(19.05%). (2)According the outcomes of all 3groups. The BMI of all cases was 24.88±3.15Kg/m2, had signifcant differences with controls(23.81±2.87Kg/m~2) (P＜0.05); but the value of total cholesterin, glycerinate, HDL-C, HDL-C, glucose, and serum uric acid of all cases had not signifcant differences with controls (P>0.05). The BMI and total cholesterin of the 34 cases group was 24.85±3.38 Kg/m2,190.02±30.50mg/dl, had signifcant differences with controls(23.81±2.87Kg/m2,179.67±31.97mg/dl) (P±0.05); but the value of glycerinate, HDL-C, HDL-C, glucose, and serum uric acid of 34 cases group had not signifcant differences with controls (P>0.05). (3) In the risk factors of overweight, hyperglycemia and lipid disorder, the total incidence of 34 cases group was 89.07%, higher than the all cases group(77.78%), and the controls group(73.44%). (4) The incidence of fatty liver was 9.68%, the incidence of intrahepatic lipid deposition was 30.65%, in all cases group from ultrasonic exams. The incidence of fatty liver was 7.14%, the incidence of intrahepatic lipid deposition was 30.95%, in 34 cases group from ultrasonic exams. The outcomes had not signifcant differences with controls (fatty liver 17.46%, intrahepatic lipid deposition 23.81%). The incidence of BPH was 20.51% in all cases group, and 12% in 34 cases group, had not signifcant differences with controls (17.24%).Conclusions:AGA was a Mostly middle-aged disease, affected by family history, mental factors, life style and so on, was a multi-factor disease. The incidences of MS and cardiovascular events'risk factors and BPH in AGA patients with hair loss on the top of head were not higher than the incidences in all AGA patients. AGA and MS, cardiovascular events were probably related. AGA and BPH had not signifcant correlations.
|
PDF Full Text Request