Analysis Of Serum Lipid Levels Among Young Male Patients Before Percutaneous Coronary Intervention And The Relationship Between The Syntax Score

Objective:We retrospectively investigated the serum lipid levels among young male coronary artery disease (CAD) patients before percutaneous coronary intervention (PCI) and analyze the serum lipids according to Syntax scores. The relationships between lipids level and syntax scores in young male CAD patients were evaluated.Methods:A consecutive 271 patients (54±6 years old) with CAD before PCI were enrolled in this study. The patients were divided into STEMI and non-STEMI (non-STEMI and UAP) group and serum lipid levels before PCI were analyzed with Syntax scores. The Syntax score was calculated according to the results of coronary artery angiography (CAG). All of the patients were not underwent lipid-lowering therapy before in-hospitalization. The severity of coronary artery disease were divided into 3 Syntax score groups according to the Syntax scores in all patients, light score group (Syntax score<22), moderate score group (Syntax score 23-32), and severe score group (Syntax score≥33). The lipids such as TC,HDL-C,LDL-C,non-HDL-C,apoAI,apoB,LP(a),TG were studied in every groups. The relationships between lipids level and Syntax score groups in young CAD patients were evaluated.Results:1. Baseline clinical characteristics, serum lipids levels and Syntax scores were no significant differences between STEMI and non-STEMI groups in young male CAD patients.2. The serum lipids levels of LDL-C, apoB, non-HDL-C, LDL-C/HDL-C and apoB/apoAI were significantly increased in moderate and severe Syntax score group than that of light Syntax score group in STEMI patients.3. The serum lipids levels of LDL-C,apoB,LDL-C/HDL-C,apoB/apoAl were significantly increased in moderate and severe Syntax score group than that of light Syntax score group in non-STEMI patients. The TC and non-HDL-C serum levles in severe Syntax score group were significantly increased than that of light Syntax score group patients.Conclusion:The Lipids levels and Syntax scores were no significant difference between STEMI and non-STEMI young patients before PCI. Most of the patients (>82%) were distributed in the light Syntax scores group. The serum levels of LDL-C, apoB, LDL-C/HDL-C, apoB/apoAI and non-HDL-C were significantly increased in moderate and severe Syntax score groups in both STEMI and non-STEMI patients.