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The Cross-sectional Study Of Dyslipidemia In Hypertensive Adults Of Anqing Rural Community

Posted on:2011-07-24Degree:MasterType:Thesis
Country:ChinaCandidate:Z R YangFull Text:PDF
GTID:2144360305980598Subject:Epidemiology and Health Statistics
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Objective: To investigate the distribution of the lipid levels and dyslipidemia's prevalence, and investigate the main impact factors with the prevalence of dyslipidemia in primary hypertensive Anqing rural residents, it provides a scientific basis for multiple factor prevention and control to cardio-cerebral vascular diseases. Methods: Subjects aged 45~75 years old were recruited by cluster sampling from Anqing rural communities during 5/2008~10/2008. Data were collected by questionnaire and physical examination, using automatic biochemical instrument to detect total cholesterol (TC), triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) levels in serum, low-density lipoprotein cholesterol (LDL-C) values was calculated by the Friedewald formula. T-test,analysis of Variance andχ2 test , multiple Linear and Logistic regression were used to analyze the related indexes. Results:A total of 8 562 individuals (3 540 males and 5 022 females) were participated in the study, the mean±SD of TG was 1.17±0.69 mmol/L in males and 1.43±0.72 mmol/L in females, the mean±SD of TC was 4.58±0.90 mmol/L in males and 4.84±0.93 mmol/L in females, the mean±SD of HDL-C was 2.13±0.54 mmol/L in males and 2.07±0.47 mmol/L in females, the mean±SD of LDL-C was 1.90±0.73 mmol/L in males and 2.10±0.73 mmol/L in females. The means level of TC, TG and LDL-C of females were higher then males, but the mean level of HDL-C of females was lower then males, the statistical differences of all were significant(P<0.01). The prevalence of high-TC, high-TG and high LDL-C of females were 7.1%, 9.7% and 1.0%, higher then males ( 4.2%, 5.8%, 0.6%, respectively), and the statistical differences were significant (P<0.01). The prevalence of low HDL-C were 1.0% for males, 0.9% for females, but the difference was not statistically significant (P>0.05). The levels of lipid were different when the group of subjects'age or BMI or smoking were different. TG, TC and LDL-C levels were decreased with increasing age in males, but the opposite in females. The TG, TC and LDL-C levels were increased with increasing BMI, but HDL-C levels were decreased with increasing BMI, the statistical differences of all were significant(P<0.05). The lipid levels were different with different smoking status, but the difference was not statistically significant (P>0.05). The prevalence of dyslipidemia were different when the group of subjects'age or BMI or smoking were different. After adjusting for related variables, the prevalence of high-TC, high-TG were increasing when age group decreased in males. Comparison of 45 to 50 age group, 50 to 55 age group increased risk of prevalence of high TG 73% (OR = 1.73,95% CI :1.12-2 .68) in females. The prevalence of high-TC, high-TG were increasing when BMI increased, obese group in which was the highest prevalence of dyslipidemia. When BMI increased 1Kg/m2, the prevalence of high TG and high TC increased the risk of 31% (OR = 1.31, 95% CI: 1.24-1.37) and 10% (OR = 1.10,95% CI: 1.05-1.17) in males, the prevalence of high TG and high TC increased the risk of 16%(OR=1.16,95%CI: 1.12-1.19) and 4%(OR=1.04,95%CI: 1.01-1.07) in females. The statistical significance (P> 0.05) was not significant between the prevalence of high TG, high TC and different smoking status. Conclusion: The detection rate of dyslipidemia is high in essential hypertensive adults of these rural communities. It is indicated that when subjects were in the treatment of hypertension also needed to pay attention to the control of blood lipid levels. There were significant differences of lipid metabolic disorders in different age groups, control of body weight, advocate rational meals, quit smoking and limit alcohol drinking are important measures to guard against and control abnormal lipid metabolism. This study provided the latest epidemiological data with the prevention and control strategies of hypertension, hyperlipidemia, cardiovascular and cerebrovascular disease for our country.
Keywords/Search Tags:essential hypertension, dyslipidemia, cross-sectional study
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