Studies On The Effection Of Rougan Granules On The Serum TIMP-1 Expression Of Liver Fibrosis Patients

Objective:â‘ Observation of liver fibrosis patients serum powder TIMP -1 content.â‘¡The patients were observed after taking the liver granule, and discusses symptoms improved treatment of liver fibrosis powder mechanism.Methods: 60 cases with into the standard type stomach, liver fibrosis were randomly divided into the treatment group and control group, 30 cases in treatment group with liver Fried granule oral treatment, the patient oral pill bug, sting rhubarb treatment course for 6 months, the two drugs to compare with TIMP-1 before and after the treatment of serum content changes and the main symptom, disease, liver, kidney change.Results:â‘ TIMP-1 before and after the treatment of serum content determination, two groups of serum TIMP-1 in treatment before dropped significantly, statistically significant (p< 0.05), the difference between the two groups was statistically significant (p>0.05).â‘¡In treatment group and control group after treatment, clinical symptoms were obviously improved, the treatment group than in control group, the group was statistically significant differences between the comparison group (p<0.05). During the course of treatment of liver granule that stalking rib pain, abdominal distension, eat less obvious improvement of symptoms.â‘¢Two cases after treatment, the AST level is healing ALT there before declined obviously (p< 0.05), but the group compared with no significant differences between (p> 0.05).Conclusion:â‘ Liver powder can be reduced to a certain extent in patients with hepatic fibrosis TIMP serum content;â‘¡Liver powder can improve liver function, reduce serum ALT levels;â‘¢the AST, Patients with hepatic fibrosis effectively relieve the symptoms and signs.