Effects Of The Balance Between ACE-Ang-AT₁ Axis And ACE2--Ang-(1-7)-MAS Axis On Heart Failure

Renin-angiotensin system (Renin-angiotensin system, RAS) and cardiovascular disease development are complex and closely linked. In recent years, found some new members of RAS: angiotensin-converting enzyme (ACE) 2, Ang-(1-7), Ang-(1-7) receptor MAS.Which ACE2, Ang-(1-7) and MAS constitute a new branch of RAS:ACE2-Ang-(1-7)-MAS axis, with the previous ACE-Angâ…¡-ATI antagonist axis relative to the multiple role of the two The balance between the heart failure may have a complex impact, which for the treatment and prevention of heart failure provides a new strategy.