Study Of Preparation And Quality Standard On Zhitejia Suppository

Sore as hemorrhoids, anal fissure, anal fistula, rectal prolapse, constipation, blood in the stool and other anorectal diseases commonly known, is the particular common disease. Incidence of any age can be, which is common in people aged 20-40, and may gradually increase with age increase, therefore, "Ten nine hemorrhoids," said. Hemorrhoid suppositories are some of my special good clinical efficacy with the exact prescription hemorrhoids particularly good tablet made on the basis of the traditional Chinese medicine, the drug prescribed by the Sophoricoside (fried), Sanguisorba carbon, skullcap, angelica, Citrus aurantium, wind, tannins, composed of donkey-hide gelatin Bawei medicine. Suppository can reach lesions, thereby enhancing the local concentration, strengthen the antimicrobial activity, improve efficacy, shorten treatment, reduce adverse reactions and so on.With the guidance of the theories of Traditional Chinese Medicine and Pharmacy (TCMP), Zhitejia Suppository has been studied on preparation procedure and quality standard by the modern scientific method. Huaijiao Zhiqiao Danggui and Baicalin were identified by TLC. Baicalin was assayied by HPLC,column:Kromasil C18柱(4.6 mm×200mm,5μm); flow rate was 1.0ml·min-1;the column temperature was 30℃;the mobile phase:methanol-water-phosphoric acid(45:55:0.2);and the detection wave length was 275nm., the method is simple, accurate and reproducible, It can be used for quality control of Zhitejia Suppository.The study of Traditional Chinese Medicine Theory, as tested by means of modern technology, particularly good for the hemorrhoid suppository dosage form provides a new quality evaluation method.