Pharmaceutical Research Of Xiang Lian Hemorrhoids Suppository

This topic is in the traditional Chinese medicine theory, application of modern pharmaceutical technology, the suppository has been researched on pre clinical pharmacy. According to the physicochemical properties of the functions and indications of the prescription ingredients, determine the dosage form, the development of a process line, by the central composite design-response surface method in prescription drug extraction, purification and concentration and process for screening, extraction method and the optimum conditions are determined. At the same time the corresponding investigation of concentration, process conditions and materials, the preparation process was determined. The aroma of hemorrhoids suppository.Study on the quality standard of the preparation, the other six drugs were studied by TLC, the Coptis chinensis, Galla chinensis, borneol, frankincense identification method is simple, reproducible and good specificity and quality standard of income. HPLC determination of berberine hydrochloride in Rhizoma Coptidis in other official medicine, conducted a systematic methodology, the results are consistent with the requirements, according to the determination results of batches of samples, making the limit of the content of berberine hydrochloride, the berberine hydrochloride each containing small not less than 12mg.The preparation, the long-term stability of accelerated stability test, the quality control standards on the basis of the results showed that:the preparation process is reasonable and feasible, the quality control standards, product quality stable.