Testosterone Undecanoate To Rats Anus Levator Skeletal Muscle Satellite Cell Androgen Acceptor's Influence

Objective Discussion different density androgen to skeletal muscle satellite cell's function and to androgen acceptor's influence. Methods Primary cultured skeletal muscle satellite cells, and identified cells,by different concentrations of testosterone(0.01×10-3ng/ul,0.04×10-3 ng/ul,0.16×10-3ng/ul,0.64×10-3ng/ul,1×10-3ng/ul)on skeletal muscle satellite cells, determining of the growth curve of skeletal muscle satellite cells, cell number and the content changes in target cells of androgen receptor. Results In the women's normal physiological range, with androgen concentration increases, cell number increase, value-added accelerated, androgen receptors expression level has a gradual rise trend. However, different concentrations of androgen on the role of skeletal muscle satellite cells is not significant. Conclusions Androgen function after anus levator skeletal muscle satellite cell, displays the androgen promotion skeletal muscle satellite cell multiplication and the AR expression. In the feminine androgen physiology dose range, along with androgen density's increase, the promotion cell multiplication which and the AR expression function the androgen expresses is stronger.