Clinical Study Of Yangrenqubi Decotion Adjuvant Treatment On The Spleen And Stomach Deficiency Ankylosing Spondylitis

ObjectiveThe research is based on a common clinical disease ankylosing spondylitis (AS). AS disease, the crowd mostly middle-aged, often leads to deformities, seriously affecting the quality of life of patients and the ability to work, and treatment is difficult. Therefore, the disease has been the focus of the study by experts and scholars. Based on years of clinical experience, combined with the historical literature, my tutor insists that the hot and humid South, the Lingnan region to the spleen and stomach deficiency human body easily. "essence infirmity and appearance eusthenia, tendon and vessel lose support, humid heat hinder tendon and vessel " is the key to the pathogenesis in Guangzhou and its surrounding coastal area. And the treatment of this disease by early and late stages of the treatment. Early ankylosing spondylitis is more responsible for the real evil, and " eliminating humid heat, invigorating the kidney and blood, keeping tendon and vessel soft and smooth " is the basic treatment of regulation, with Sansi Decoction as the basic treatment, reflecting the treatment of patients with multiple good results. The middle and late ankylosing spondylitis and spleen deficiency ferrite is more from the stomach deficiency, by the rule in the spleen Qi, dependent on the homemade Qubi docotion, treatment of the actual situation in the middle and late stages of Ankylosing spondylitis, and often achieve good clinical results. In this randomized, parallel control study, through Clinical Observation on adjuvant therapy of Syndrome differentiation and treatment of Traditional Chinese Medicine on AS, and explored the pathogenesis, treatment, prescription drug laws of treatment of Traditional Chinese Medicine on AS, provided a theoretical basic and clinical basic programs for the formulation of Syndrome differentiation and treatment of Traditional Chinese Medicine on ankylosing spondylitis.MethodsIn this study, the clinical diagnosis of spleen deficiency select ankylosing spondylitis patients as the research object, a prospective randomized controlled trial, according to experimental groups:control group =1:1, a total of 40 patients were obtained randomly by checking random number table, After screening, patient treatment time by a simple randomized dependents were given oral Yangrenqubi Doctotion, nimesulide capsules and sulfasalazine tablets; basic treatment with nimesulide capsules, sulfasalazine tablets; basic Treatment. In strict accordance with the requirements of this experiment, a total of 40 patients were collected. Two groups of patients had no loss.ResultsTwo groups of patients before the general information including age, gender, disease duration, the main disease, second disease, the overall function of grading, the difference had no significant (p>0.05), consistent baseline before treatment.The two groups before and after treatment, respectively, scores, test group of patients in clinical symptoms after treatment, the overall function, laboratory parameters and other aspects to improve the situation significantly improved compared with before treatment, the difference was significant (p <0.05); control Group of patients in clinical symptoms after treatment, the overall function, such as the improvement of laboratory parameters were also significantly improved compared with before treatment, the difference was significant (p<0.05); test group and control group before and after treatment sacroiliitis x Ray classification did not change, the difference was not statistically significant (P> 0.05), while changes in the pillow away from the wall than the two groups before treatment, no significant improvement (p>0.05).Two groups of patients'rates of improvement after treatment compared with clinical symptoms of which to the overall function, laboratory parameters to improve the situation, the experimental group than the control group between the two groups were significant (p<0.05), while the pillow wall The degree of improvement from the other side, had no significant difference (p> 0.05).ConclusionYangrenqubi Decotion's adjuvant treatment of stomach Qubi deficiency ankylosing spondylitis, can significantly improve symptoms, improve the patient's life and work abilities. For the diagnosis of spleen deficiency in patients with ankylosing spondylitis, application of Yangrenqubi Decotion intervened in improving symptoms and delaying disease progression and improve quality of life of patients and achieved a better clinical efficacy, is worthy of clinical and Further study.