| As a major cardiovascular disease, CHD had been one of a serious threat to human health and life, in recent years in China the morbidity and mortality of CHD also increased year by year. Currently with PCI, mainly including within the PTCA and STENT, and CABG widely used in clinic, which greatly reduced the incidence of patients' cardiovascular events, and improved the patients' clinical symptoms. Comparing with CABG, PCI was a minimally invasive surgical intervention, with easy operation, low surgical risk advantages, fast postoperative rehabilitation, distinct curative effect, more patients will accept.Though PCI had effectively improved the myocardial ischemia in patients, but large clinical observation showed that some patients still had chest pain after interventional treatment, and poor quality of life etc. The clinical studies showed that, the reasons causing postoperative chest pain are complicated, including stent restenosis, subacute thrombosis, side branches occlusion and distal embolization, incomplete reasculari- zation, slow coronary flow phemonenon, SCFP (no-reflow phenomenon) and rapid arrhythmia, stenting reaction and mental factors. There existed a knowable pathological mechanism of complex after PCI, so PCI was just one of the important treatments. Continue treatment ater PCI should be also gived enough attention, that whole therapy was the optimal solution.While the overall, syndrome differentiation therapeutic principles of TCM can be a very good compensate for the poverty of interventional treatment. In recent decades, TCM workers in the syndrome differentiation and treatment after PCI had a lot of researches, like the TongGuan capsule, qi and promoting blood circulation medicine, YiXin drink, DengLao capsule for CHD such intervention medicine. In researches there involved syndrome types, including blood stasis, deficiency syndrome, sputum turbidity certificate, qi stagnancy certificate, HanNing certificate and etc. And blood stasis the most common after two weeks of PCI. So for CHD patients with blood stasis after PCI, discusse how its treatment and the relevant mechanism, get safety, health, effective treatment methods was especially important, for accumulating some experience of Chinese medicine treatment in intervention.ObjectivesObservate blood stasis scoring, TCM symptoms score and the various platelet parameters of ShuXueTong injection on CHD blood stasis patient after PCI, and explore its influence of various platelet parameters, clinical efficacy and safety evaluation.MethodsFrom the heart center of Guangdong hospital of traditional Chinese medicine, selecte 60 cases of patients up to standard after PCI. According to the simple random method 1:1, divide them into the treatment group and the control group.30 cases were randomly divided into ShuXueTong group, another 30 cases. Record respectively, before treatment and two weeks later, the two groups of cases'blood stasis scoring, the TCM symptoms score, platelet parameters (PagT, PLT, MPV, PDW, PCT, L-PLT, MPC), and other laboratory testing index (including blood clotting, electrocar- diogram, troponin, liver and kidney function, etc.). And using SPSS16.0, data were statistically analyzed.ResultThe baseline data of Two groups, including gender, age, smoking history, dyslipidemia history, history of diabetes, hypertension history and the PCI operation conditions, has no significant differences. (1) ShuXueTong group and control group have no obvious difference of PagT before the treatment, comparable, after treatment all were significantly lower, difference was statistically significant (P<0.01 or P<0.05), ShuXueTong group was lower than control group (P<0.01); And PLT and PCT of two groups rise significantly, ShuXueTong group was better (P<0.05), and the MPC, MPV and PDW reduce (P <0.01). (2) blood clotting:the FIB APTT and PT of two groups before treatment were comparable. ShuXueTong group'PT, APTT extensed after treatment, FIB declined. Between them the treatment group was more significant. (3) TCM symptom scores of the two groups after treatment has obviously improved, comparable (P<0.01 or P<0.05). ShuXueTong group in aspects, such as chest pain, back ache, was better than control group, comparable (P<0.01 orP< 0.05). (4) After treatment, blood stasis scoring of the two groups has obvious improvement than before (P<0.01), ShuXueTong group had a better data. (5)Kidney, liver meritorious service and electrolyte of ShuXueTong group after treatmentz were no difference obviously (P>0.05). Compared with control group, was no difference (P>0.05), has the good security.
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