Objective:Observe the clinical curative effect of Bu Shen Yi Jing HuoXue Fang,which is applied to treat POF, and explore its work mechanism.Methods: We totally observed 40 patients of POF and it was divided into two groups randomly. The treatment group take Bu Shen Yi Jing HuoXue Fang, while the control group takes Jiarongpian,which are compared to observe their curative effects and impacts on Follicle stimulating hormone (FSH) Luteinizing hormone (LH) and Estrogen hormone (E2).Results: After treatment, the syndrome score of the two groups has significant differences (P <0.05). The FSH level and the LH level of the two groups are both obviously decreased after treating, which has significant differences compared with its original level (P <0.01) and the control group (P <0.01 or P<0.05). The E2 level is increased of the two groups after treating, which has significant differences compared with ex-treatment (P<0.01) and the control group (P<0.01).Conclusion: Bu Shen Yi Jing HuoXue Fang has better effect in treating POF. The mechanism may be related to kidney essence and blood activating may improve the endocrine level, increased the E2 level ,decreased the FSH level and the LH level ,so the symptoms are improved.
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