The Assessment Of The Cardiac Muscle In Patients With Dia-betes Mellitus, And Combination With Hypertension By The Tissue Doppler Imaging

Objective:Application of the Ultrasonic Cardiography and Doppler tissueimaging technical to elevate the heart Structure and systolic and diastolic heart function of diabetic patients with hypertension and diabetes in patients, thereby revealing both diabetes and hypertension on the risk of heart.Methods:1. Choice of type 2 diabetes (diabetes mellitus, DM) patients as theexper imental group,103 cases, such patients will be divided into two sub-groups:normal blood pressure in diabetic patients subgroup (DM) 50 cases and diabetic patients with hypertension subgroup (DM+HP) 53 cases. At the same time,50 cases of ele ction as a normal physical examination and normal control group (NC).2. GE Vivid 7 ultra sound diagnostic applications, the conventional two-dimensional echo car diography, conventional measurement data including the left atrial cardiac diameter (LA), inter ventricular septum thickness (IVS), left ventricular posterior wall thickness (LPW), radio blood fraction,Ecalculated left ventricular mass index (LVMI), the conditions and then transferred to TVI, respectively, of left ventricular wall, posterior septal, posterior wall, the former interval, inferior and anterior wall of the six loci peak sys tolic mitral annular velocity (Sa), peak early diastolic velocity (Ea), peak late di astolic velocity (Aa), each measuring 3 parts averaged cardiac cycle and calculation of the early diastolic and the late peak velocity ratio (Ea/Aa), tei index.Results:1. Transthoracic two-dimensional measurement value:group of diabetic patients wi th normal left ventricular two-dimensional control group comparison test:diabetes me llitus group (DM) and normal control group (NC) Comparison of left atrial diameter (LA), interventricular septum thickness (IVS), left ventricular posterior wall thickness (LVPW), ejection fraction (EF%), no statistical significance. Left ventricular mass in dex (LVMI) compared with the normal increase in the control group, p<0.05. normal blood pressure in diabetic patients with hypertension sub-two group of diabetic patien ts with sub-group comparison of left ventricular-dimensional measurement: the comb ined subgroup of patients with high blood pressure diabetes (DM-HP), interventricula r septum thickness (IVS), left ventricular posterior wall thickness (LVPW) and left ve ntricular mass index (LVMI) in diabetic patients with normal blood pressure subgroup (DM-NP) were relatively higher, p<0.05. left atrial diameter (LA) and Ejection fractio n (EF%) was not significant between the two.2. Mitral annulus in each group measured value that points:Experimental group, experimental group, two sub-group and control group mitralannular sites of the six tissue velocity measurements in each group wall, inferior wall, posterior wall velocity than interval, anterior, and maximum wall velocity.3. Diabetic group and control group mitral annulus measured values that point: the whole diabetic group velocity in the peak early diastolic mitral annulus velocity (Ea), peak early diastolic mitral annulus velocity/peak late diastolic mitral annular velocity (Ea/Aa) than those in the control group to reduce the, p<0.05. Interval after the diabetic group, lateral, anterior, inferior, posterior wall of the former interval and peak early diastolic mitral annulus velocity (Ea) than those in the control group reduced, p<0.05. Wall peak late diastolic mitral annular velocity (Aa) higher than the control group, p<0.05. normal blood pressure and hypertension in diabetic sub-group of diabetic subgroups that point measurements of mitral annulus value:normal blood pressure and hypertension in diabetic sub-group of diabetic sub-group mitral annular velocity was no significant overall difference. Diabetes high blood pressure before the interval Aa subgroup than normal to reduce blood pressure in diabetic sub-group, p <0.05.4. Tissue Doppler systolic and diastolic indexes measured value Systolic function indicators of inter-group comparison:diabetic group and control group, hypertension, diabetes subgroup than normal blood pressure measurement in diabetic sub-group comparison Sa no significant difference, p>0.05.butSa hypertension diabetes subgroup than the other two groups to reduce the trend. Indicator of diastolic function between groups comparison:Ea measured diabetes group than the control group to reduce the value, p<0.05; Aa values higher than the control group, but no significant difference p>0.05; Ea/Aa ratio than the control group reduced, p<0.01. Ea diabetic hypertension subgroup values, Aa measured value and the Ea/Aa ratio of diabetes with normal blood pressure subgroups was no significant difference, p>0.05.5. Diabetic group compared with the control group increased Tei index were 0.58± 0.13 and 0.34±0.05, p<0.01, diabetic group in Central Asia no significant difference between groups, p>0.05.6. Correlation analysis:Diabetes duration and Ea/Aa-related analysis showed that: the course and the Ea/Aa was negatively correlated with the course of Ea/Aa r=-0.655, p<0.05 (bilateral); the level of glycosylated hemoglobin (GHb) and Ea/Aa correlation analysis Showing:GHb and Ea/Aa was a negative correlation, GHb and Ea/Aa r=-0.621, p<0.05 (bilateral).Conclusion:1,The diabetic patients with higher body mass index and lipid levels, and the presenceor absence of hypertension did not show a clear impact on their.2,The diabetes group with thickened wall and increased left ventricular mass index than in the control group, The blood pressure of hypertension sub-group was significantly higher than normal blood pressure subgroups, indicating that high blood pressure due to increased cardiac afterload may be a major factor.3,The diabetic patients of mitral annulus velocity that point performance for the wall, inferior wall, posterior wall velocity than interval, anterior, and lateral velocity of the largest similarity with the control group.4,The 2 diabetes subgroup Ea/Aa was no significant difference, is significantly lower than the control group, suggesting that elevated blood sugar impact on diastolic function in blood pressure and may even be worse.5,The level of glycosylated hemoglobin (GHb) and Ea/Aa Correlation analysis showed a negative correlation with diabetes duration and Ea/Aa Correlation analysis showed a negative correlation.6,Early diabetic patients the incidence of diastolic dysfunction occurs earlier than the contraction of the obstacles, at the same time the original high blood pressure can increase the myocardial damage of diabetes.