Applicable Study Of DTI In Brain Neoplasms

Purpose: To evaluate the role of diffusion tensor imaging (DTI) in the differentiation of these cerebral tumors and to investigate the value of diagnosis with regard to apparent diffusion coefficient(ADC) and fractional anisotropy(FA). Methods: The study had 39 case of brain neoplasms, inclding 12 case of glioma, 10 case of meningioma, 8 case of lymphoma, 9 case of neurinoma. All case were confirmed by pathology after surgery. By reconstrusting color-tentor, we choose the solid area of tumors as region of interest (ROI) and measure ADC and FA of ROI. The differentiation of ADC and FA among the four types of tumors were analyzed. To reconstruct chief nerve fiber bundle which surrounding tumors by diffusion tensor tractography(DTT), mix together with tumors and observe the shape of fiber. Results: ADC of neurinoma is highest, and FA of meningoma is highest. ADC and FA between neurinoma and Meningoma has significant difference(P<0.05). ADC of lymphoma is lowest, and has significant difference with glioma(P<0.05), but FA has not significant difference(P>0.05). White matter fiber of surrounding tumors have three shape, including compression with shifting, inflitration and destruction before surgery. After tumors were cutted, shifting of white matter fiber recovered almostly, inflitration and destruction with white matter hardly changed compared with preoperative. Conclusion: Characteristics of ADC and FA with brain tumors have significant difference. It could be described precisely relationship between tumors and white matters and the shape of fiber including preoperative and afteroperation by using DTT.