| A number of violent crimes disturb the social stability, and it is a prominent problem in our society. So the study about that the way violent crimes come out is an important direction of research and development. In foreign, a large number of criminal behavior studies verifyed that some types of crimes are closely related to certain genes of emotion regulation. In the same time, some studies confirmed that crime is mainly affected by family and social environment. As we all know, genes are regulated by environment, so the study of crimes, especially violent crimes, is related to the study of biological characteristics. Also, the way how different living environment affects is very important to understand why crimes come out.With the emotional impulse of the important genes MAOA-VNTR as the index to analysis the polymorphism of genetic, we use the Eysenck Personality Questionnaire to analyse psychological characteristics, considering the family income of prisoners, education and profession as environmental factors. Using the data mining analysis to analyze the relationship between gene-environment-psychology and Chongqing prisoners (intentional homicide, rubbery, rape, intentional injure), we offer some help to the investigation of biological effects of violent crimes and the prevention and control of violent crimes.The study was approved by the Ethics Committee of the Health Science Center, Dalian Maritime University. The test group(624 violent crimes) were recruited from a Chongqing prison and a Chongqing juvenile detention. The control group (609 normal person) was recruited from normal population in Chongqing. Our sample who gave consent to participate in the study underwent the assessment process. To be included in the study, All participants fill background questionnaire and psychological questionnaire. The DNA fragments of MAOA-VNTR were all measured using PCR and capillary electrophoresis. They are verified by sequencing. Both allele frequencies and genotype frequencies in two groups were compared. The study was to determine the association between MAOA, environmental factors and psychological factors in man with violent behavior by the rough set.The MAOA is an important metabolic enzyme in the monoamine neurotransmitter of the human brain. The MAOA gene is a polymorphic gene that is found on the X chromosome.The polymorphism arises from a 30 base pair variable number of tandem repeats upstream in the 5'regulatory region of the gene. There are MAOA alleles that contain 2,3,3.5,4, and 5 repeats of the 30bp sequence in the MAOA promoter. Recently, MAOA VNTR was identified in the promoter region of the MAOA gene, which was shown to be associated with MAOA transcriptional activity. The enzyme activity coded by the gene with 3-repeat sequences is much lower than the other genotypes.According to functional features, the'allele 1'with 3 repeats contributes to low MAOA activity while the other'allele 3'with 3.5 and 4 repeat units represents high MAOA activity.The PCR products included five alleles of 30bp MAOA-VNTR:2,3,3.5,4,5, with the most common being the 3 and 4. No significant difference were found in allele frequencies when violent crime group was compared with controls (P>0.05). In Eysenck Personality Questionnaire, using the neuroticism factors and emotional stability for evaluation index, we find the p value between college students of control group and test group is lower than 0.05, which indicated that psychological factors on juvenile delinquency were significantly associated.Ultimately, the application of rough set data mining association analysis indicated that violent crime may be related to the following factors:lower than middle income families, secondary school culture or below, neuroticism and psychoticism dimensions deviating from the normal dimensions,3 or 4 tandem repeat sequences of the MAOA genotype. The enzyme activity coded by the gene with 3-repeat sequences is much lower than the other genotypes, resulting in the efffect of the serotonin transporter (5-HT)system metabolism. It's already reported that 5-HT metabolism disorder is closely related to aggressive behavior and violence. Although that showed no difference between normal and control groups just from the gene aspect, with the analysis of the relationship between psychological characteristics and living environment, we found that violent offenders from Chongqing, with 3 or 4 tandem repeat sequence MAOA genotypes and worse family environment and education, neuroticism and psychoticism dimensions deviating from the normal dimensions, are prone to violent crime.
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