The Influences Of Different Exercise Modes On The Bone Mineral Density, Biomechanics, And Metabolism Of The Ovariectomized Rats

Objective: In order to explore the influence of different exercise modes on the bone mineral density(BMD), biomechanics performance, and metabolism index of the ovariectomized rats. Method: 32 three-month SD female rats were simulated and ovariectomized to establish the model of osteoporosis. They were divided into four groups: simulated contrast group, quiet group, swimming group, and jumping group. By measuring the weight, bone metabolism BMD of hind limb femur and vertebra, and biomechanical properties, We have studied the influences of medium-intensity swimming and jumping on the skeleton of ovariectomized rats. Experiment results:1. The experiment successfully establishes rats' of high turnover osteoporosis.2. An exercise intervention can inhibit the rapid increase in weight; optimize the content of blood bone metabolism of the ovariectomized rats at an early period. After the experiment, the weight of the two exercising groups is obviously lower than the quiet group, which proves that exercise can inhibit the rapid increase in weight. However it can't offset the ovariectomized impact on weight. The content of Ca in the serum of the two exercising groups is obviously lower than the quiet group(P<0.05), the content of P is relatively high(P>0.05), the content of AKP is relatively low(P>0.05); The content of STR-ACP of the two exercising groups is higher than the quiet group, and the jumping group is obviously higher than the quiet group(P<0.05).3. Exercise can reduce bone loss in ovariectomized rats, inhibit decline in bone biomechanics. After the experiment, the BMD of femur and vertebra of the two exercising groups becomes higher, but it is still lower than the simulated contrast group, which shows whether swimming or jumping movement for reducing bone loss in rats have played an active role but they can not compensate for the loss of bone mass in the ovariectomized. Vertebra and femur biomechanics properties of the jumping group are obviously higher than the quiet group. The effect on the swimming group is also improve but not so obvious.4. The jumping group is better than swimming group in almost all the indicators.Conclusion: Jumping is more effective in improving the skeleton performance ofthe ovariectomized rats than swimming, so it can be more effective in preventingthe occurrence of osteoporosis.