Clinical Observation On Treatment Of Advanced Lung Cancer By Radiotherapy Combined With Kangai Injection

Objective: Using Kang Yi injection in combination with radiation and chemotherapy in the treatment of non-small cell lung cancer research.Methods: In March 2012 to March 2014 in our hospital diagnosed with locally advanced lung cancer during the period of two years, 120 patients diagnosed of non-small cell lung cancer. Do prospective cohort study of 50 cases were divided into observation group and control group 40 cases, control group adopts radiotherapy plus DP chemotherapy regimens for 5 times per week, on the basis of the observation group in the control group using Kang Yi injection treatment, both groups in 21 d, for one treatment cycle, treatment evaluation of curative effect, symptom improvement after 2 cycles, adverse reaction and quality of life index.Results: Efficient in the observation group(CR + PR) was 32.0%, the median surial 10 months. Effective rate of group B(CR + PR) of 25.0%, the median surial was 8.2 months. Median surial compared there was no statistically significant difference(P > 0.05), the efficient and total effective rate compared with the observation group was obviously higher than that of control group, with statistical significance(P < 0.05); Symptom: the two groups after treatment group in pain relief, weight gain, cough reduce and chest tightness these period is obvious superior to control group, compare the difference was statistically significant(P < 0.05), the observation group and control group comparison of adverse reaction, the incidence of Ⅰ ~ Ⅳ level had no obvious difference, no statistical significance; The two groups after treatment in terms of the overall quality of life situation, period Kang Yi group was 44%, 25% higher than that of non Kang Yi group, with statistical significance(P < 0.05). Major adverse reactions in both groups were marrow suppression, gastrointestinal reactions. The observation group in the bone marrow inhibition of 18 cases, control group 30 cases. Is similar between the two groups was statistically significant(P < 0.05).Conclusion: Kang Yi injection combined radiation and chemotherapy scheme can enhance the middle-late stage lung cancer cells and immune function, reduce the side effects of radiation and chemotherapy, improve the patient’s quality of life, is worth popularizing in further clinical use.