Clinical Study On Serum SOD And TNF - α In Patients With Phlegm - Dampness Obstructive Sleep Apnea Hypopnea Syndrome

Objective: To study the correlation between serum SOD, TNF- and related indexes in phlegm dampness patients with obstructive sleep apnea hypopnea syndrome and healthy subjects. Methods: Income between January 2012 and January 2014 in the people’s liberation army 463 hospital in phlegm constitution patients with obstructive sleep apnea hypopnea syndrome 40 people and set it for phlegm constitution OSAHS group(19 males and 21 females, the average age range is 41.15±8.23), and randomly selected from the same time period in this hospital physical examination of healthy subjects 40 people, These 40 people will be as healthy group(20 males and 20 females, the average age range is 40.07±9.36years), the two groups of subjects age were no statistically significant differences(P < 0.05).All into the group of people in the exclusion of 1 weeks with upper respiratory tract infection 、acute bronchitis and other indicators of the impact of airway diseases Or the presence of severe cardiovascular, liver, kidney and other diseases in patients with systemic diseases., Epworth sleepiness scale(ESS) and multiple sleep monitoring in all subjects,Monitoring nocturnal sleep oxygen saturation(SO2), low ventilation index(AHI) and other indicators,Chinese constitution and decision table will be complete after monitoring,Morning blood tests for serum SOD and TNF- α.Analysis and comparison between the phlegm constitution OSAHS group and the healthy group. Results: Comparison of phlegm dampness OSAHS patient group and healthy group,serum SOD、TNF- α、Neck circumference, waist circumference and body mass index(BMI) and hypopnea index(AHI) and nocturnal oxygen saturation saturation(MSO2) and Epworth Sleepiness Scale(ESS) scores were statistically significant.All the subjects abdominal circumference was positively correlated with SOD. Conclusion: Compared with healthy subjects, phlegm dampness OSAHS patients with serum TNF-α, SOD and related indicators were significantly different.Whether serum SOD and TNF- α can be used as predictors and treatment of phlegm dampness OSAHS.Early intervention on the patients with abnormal index,prevention of the occurrence and development of disease,There is yet to be further studied.