Polyphenols Spirulina Tablets

Based on Tea polyphenol's antioxidant and Spirulina's immune enhancement which contains rich spirulinaβ-carotene, vitamin E that have a synergistic reaction with Tea polyphenol, Tea polyphenol Spirulina tablet is prepared by its certain combination. This health-care food is antioxidant and play a role of enhance immune suitable for the middle-aged and elderly and inhance Tea polyphenol's antioxidant.First of all, the preparation of tea polyphenol and spirulina tablet is studied. Using collapse time, grain's properties, stiky model properties and tablet's glabrous'degree as indicator, the formulation preparation technology is optimized by single element experiments. At the end, tablet's core is coated by a film which can protect tablet from wet and oxidation. The optimal formulation preparation technology are as follows: mixed Tea polyphenols, Spirulina, starch, carboxyl methyl starch sodium and magnesium stearate, then this powder is prepared to be damp mass by ethanol of 90 percent, then granulation, dryness, ground, add carboxyl methyl starch sodium and magnesium stearate, mixed uniformly, pressed and coated. A series of samples are prepared for quality criterion study and stability study. The result showed that the formulation of the dosage form is reasonable, simple.Secondly, the tablet's quality is determined based on "People's Republic of China Pharmacopoeia" in 2005 in order to control the quality of tea polyphenol spirulina tablets. As a result, surface is integrity and glabrous, rigidity, weight difference and collapse time are qualified. And the methods of tea polyphenols detected by ultraviolet spectrophotometry, epigallocatechin measured by high performance liquid chromatography andβ-caroten determined by high performance liquid chromatography are established. Then the methods are studied systemly. As a result,they are simple, exact, quick and credibly. They all can be used to determined corresponding components'content.Finally, the tea polyphenols spirulina tablet's stability is studied. Its experiments show that the tablet is affected by bright, high temperature, but still stability under high humidity. So the tablet should be put in shady and cool.