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Cd <sub> 4 </ Sub> 4v7/v8 Expression In Bladder Transitional Cell Carcinoma And Its Clinical Significance

Posted on:2001-04-27Degree:MasterType:Thesis
Country:ChinaCandidate:B D HanFull Text:PDF
GTID:2204360002952300Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective To study the clinical significance of expression of CD44v7/v8 protein in transitional cell carcinoma of bladder. Methods By using SP immunohistochemical method with anti-CD44v7/vS monclonal antibody, the expression of CD44v7Iv8 I 42 specimens of transitional cell bladder carcinoma and in S normal bladder tissues as control and its correlations with clinicopathologic factors were studied Results The positive expression were distributed in cell membrance and cytoplasm and stroma of bladder tumor tissues. The rates and levels of CD44v7/vg protein positive expression in bladder tumors were significantly higher than those in normal bladder tissues (Prate
Keywords/Search Tags:Bladder neoplasms, CD44, Invasion, Immunohistochemistry, Recurrence, Prognosis
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