Objective To investigate the effects of polyclonal hen-egg-yolk antibodies(IgY)to S.mutans and S.sobrinus on streptococcal adherence arid its best adherence-inhibiting concentration. Methods applying the specific JgY antibodies purified from the egg-yolk laid by the hen imm i tnized with S .mutans MT6R (serotype c)S .sobrinus 6715 (serotype g) attd Freud adjuvant,and marked S.mutans MT6R and S.sobrinus 6715 with to investigate the IgY antibodies of different concentration on these two streptococcal~dherence to saliva-coated HA by diluting the antibodies in the way of 1:1,1:2,1:4,1:8,1:16,1:32 in vitro. Results The results showed that the IgY antibodies with a concentration of 1:1,1:2,1:4,1:8,1:1 6,could significantly inhibit S. rnutans,S.sobrinus and S.mutans+S.sobrinus to adhere to S-HA resp cctively (p |