With Iga Nephropathy Syndrome Differentiation Typing And Clinical Correlation

IgA nephropathy is a kind of glomerulonephritis commonly seen in world. It isone of the leading causation of renal failure. The study of its pathogenesis is the mostactive and plenty field of all renal diseases. As its pathogenesis is not clear, there is nospecial druggery so far. Many doctors of TCM studied the pathogenesis, differential ofsymptoms and signs and cure method of IgA nephropathy from the age of treating it bytraditional Chinese drug in 80s. This article is divided into tow parts. The first part is theoretical study. IgANephropathy's Study of Traditional Chinese Medicine summed up the study of thepathogenesis, diagnosis and treatment based on an overall analysis of the illness andthe patient's condition, treatment by traditional Chinese medicine and westernmedicine, the relation of differential of symptoms and signs and renal pathology andexperiment by traditional Chinese medicine within recent 10 years. IgA Nephropathy'sStudy of Modern Medicine summed up the study of the epidemiology, pathogenesis,renal pathology, treatment and prognosis by modern medicine in recent years. The second part is clinical research. The purpose is to study the relation ofsyndromes and clinic, and to conclude the state of an illness and prognosis and to guidethe treatment according to the study. According to The Guide Principle of ClinicalStudy of New Traditional Chinese Drugs of Chronic Nephritis, 53 patients are dividedinto three syndromes, that is type of deficiency of both spleen-Qi and kidney-Qi, typeof deficiency of both liver-Yin and kidney-Yin, and type of deficiency of both Qi andYin, and three incidental syndromes, that is affection of exogenous wind-heat, retentionof damp-heat in the interior, and blood-stasis obstructing in the interior. To observe therelation of the syndromes and sex, age, course of disease, evocation factors, clinicalindex, pathological parameter and pathological level. The result is that the type ofdeficiency of both Qi and Yin is the mostly seen syndrome. Affection by exopathogenis the main evocation factor. And the main incidental syndrome is retention ofdamp-heat in the interior. The symptom and pathology of the type of deficiency of bothspleen-Qi and kidney-Qi are the best, and the symptom and pathology of the type ofdeficiency of both Qi and Yin are the worst, P<0.05. The disease character isdeficiency in origin and excess in superficiality. The main deficiency syndrome isdeficiency of both liver-Yin and kidney-Yin, and deficiency of both Qi and Yin. Themain excess syndrome is affection by exopathogen, damp-heat and blood-stasis. Theevolvement rule of pathogenesis is from deficiency of Qi to deficiency of Yin todeficiency of Qi and Yin. The symptom and pathology aggravates gradually accordingto it.