Heat Resistant And Susceptible Granules Treatment Of Upper Respiratory Tract Infection (wind-heat Syndrome) Clinical Observation

Objective: To investigate the effect of Qingre Kanggan Chongji on upper respiratory tract infection syndrome due to wind-heat.Methods: The concurrent comparison between experimental and control group, which were randomly chosen in the clinical trial, was employed in this study. There were entire 458 systematic cases of registered outpatients, among which 332 cases were up to the established criteria and 38 patients rejected to take part in the trial. 294 cases were applied in the study. It was estimated that sample size was about 260 recipients in line with qualitative response parameter ( α =0.05, double; power of test 1- β =0.8). 294 recipients were randomly divided into two groups, 154 cases for experiment and 140 cases for control group, which began to receive the experimental treatment concurrently and respectively. The criteria of diagnosis and therapeutic effect about the upper respiratory tract infection syndrome due to wind-heat in the study was grounded in both the criteria of diagnosis and effect of internal diseases and syndromes in traditional Chinese medicine and the guideline of new drug of traditional Chinese medicine in clinical study. The experimental results between two groupswere compared in the end of trial. The responses variables were temperature, headache, swollen and sore throat while the explanatory variable was the therapeutic effect on the syndrome of wind-heat.Results: Much better therapeutic effect was displayed in the experimental group than that in the control group such as reliving the syndrome, changing the temperature and lessening the treatment period (p < 0.05). There were 154 cases in experimental group, among which 133 cases were cured, 10 got more effective result, 2 got effective result and 9 were not cured so that curative percentage was 86.36% and effective percentage was 94.16%. In contrast, 93 cases were cured, 15 got more effective result, 1 got effective result and 31 were not cured in 140 cases for control group, and curative percentage was 66.43% and effective percentage was 77.86%. Obvious improvement in temperature, headache, swollen and sore throat showed in patients' global assessment, in comparison to that of control group in the majority of the cases (Qingre Kanggan Chongji, 94.16% of the cases; YinQiao tablet, 77. .86% of the cases).Conclusion: The methods of sweating, expelling and heat-clearing, used together in Qingre Kanggan Chongji, showed much better therapeutic effect on upper respiratory tract infection syndrome and symptoms than the single sweating or heat-clearing method used in traditional clinicaltreatment.