Blood Circulation, Qi And Activating Blood Circulation Antioxidant Effects Of Experimental Vitreous Hemorrhage Discussion

Objective: Through establishing the experimental animal model of vitreoushemorrhage, compare the different mechanism of preventing and curing the Rabbit'seyes vitreous hemorrhage and the damnification to retina and vitreous between usingthe prescriptions which is for removing blood stasis by promoting blood circulationand for supplementing Qi to promoting blood circulation .Methods: Establish the vitreous hemorrhage animal model by injecting the bloodfrom the rabbit's ear-rim vein into it's vitreous. Measure the concentration of thevitreous' SOD and MDA. Compare the different mechanism of preventing and curingthe Rabbit's eyes vitreous hemorrhage in each group.Results: After completion of the model, the vitreous is full of red blood and theeye's fundus can't be visible. Three days later, black turbidness appeared. Observedblack floccules in the vitreous during 14 to 30 days and hazed of fundus. The level ofMDA in model-control group were significantly higherr than that in normal-controlgroup ( p<0.01). Reversely, the activity of SOD were lower (p<0.01). The twoprescriptions group were better than the model-control group in decreasing thelevel MDA , and enhancing the activity of SOD (p<0.01) . However, there is nodifference in else index between the group of the prescriptions for supplementing Qito promoting blood circulation and the prescriptions for removing blood stasis bypromoting blood circulation groups (p>0.05 ) .Conclusion: The two prescriptions groups can improve the vitreous' hemorrhage andthe damnification to retina and vitreous. However, the effct is similar between the twoprescriptions group.