| HBV infection is a world-wide problem. It is accounted that there are 350 million chronic HBV infectants in the world, which hit 9th of the human death caused by illnesses published by WHO recently. China is a high-incident area of chronic hepatitis which strongly threatened the health of people.Guided by the theory of traditional Chinese medicine, we explored that chronic hepatitis B is basically caused by deficiency of Zheng-qi,exogenous contamination of heat-dampness and epdemic toxin. The basic pathologic chang is conbination of heat-dampness and epidemic toxin, damage of liver, spleen, with dampness, heat, blood-stasis, epidemic toxin, as its pathologic factor. As to treatment, we mainly clear out heat-dampness and epidemic toxin,and support healthy energy to eliminate evils as well as .AIM: To investigate the effect of Qing Gan Hua Yu Qi Qing Fa in treating chronic hepatitis B.METHOD: 99atients with chronic hepatitis B were devided randomizely into treatment group (48) and control group (51) . The patients in treatment group were treated with Fu Fang Qi Zhu Pian , 4 tablets, TID. While the patients in control group were treated with lamivudine 100mg, QD .Course of treatment is half an year, and some patients could be treatmented for one year and all the patients were followed-up by half an year after treatment.RESULTS: All the symptoms were improved in treatment group (P<0.05 or P<0.01) . ALT, AST, GGT, ALP were improved in both groups (P<0.01) . HA, LN, collagen-IV declined varily in both groups (P<0.05) ,Compared with control group, Qing Gan Hua Yu Qi Qing Fa has a better effect in clinic symptom (P<0.05) .CONCLUSION: There is no difference between Fu Fang Qi Zhu Pian and lamivudine in anti-virus, improving liver function, anti-fibrosis while Fu Fang Qi Zhu Pian has a better effect in improving clinic symptom than lamivudine. |
PDF Full Text Request