Panax Quinquefolius Saponin Oxidative Alkaline Hydrolysis Product Of Research

In this thesis, the oxidative alkaline-degradation of the total ginsenosides from leaves and stems of Panax quinquefolium L. was studied. Some reaction conditions of the oxidative alkaline-degradation including reaction solvent, temperature, time, alkalinity et al. were improved. From the crude product of oxidative alkaline-degradation, 5 compounds were isolated by repeated chromatography recrystallized methods. On the basis of spectroscopic analysis (UV, IR, NMR, MS) and physico-chemical characters, the structures of them were identified as: 20(S)-protopanoxadiol (1), 20(S)-protopanoxatriol (2), 24 (R)-ocotillol (3), dammar-20S,24R-epoxy-3β,12β,25-triol (4) anddammar-24-de-isopropyl- 12R,24R-epoxy-20S,24R-epoxy-3β-ol (5). Compound 4 was obtained from alkaline-degradation products for the first time and compound 5 was a new compound.