Pharmacodynamics Of The New The Xuan Baicheng Gas Capsule Treatment Of Pneumonia (hyperactivity Fushi)

[Aim] In modern medicine,acute pneumonia,peribronchitis,acute bronchitis etc. acute inflammatory affection of the lung belong to wind-warm retention of pathogenic heat in the lung.The disease is caused by the virus of pathogenic wind-heat and can be seen all year round, especially in winter and spring it is always the epidemic febrile disease caused by febrile disease. At present,it is treated by the effective antibiotic in Western Medicine, the treatment of pneumonia still faces with many problems and severn challenges with the change of the pathogen and the increase of drug resistance of the antibiotic, especially the symptoms of constipation caused by pneumonia hyperthermia can not be solved by the antibiotics. Abundant experiences have been gathered in Traditional Chinese Medicine, It has advantages of diagnosis and treatment based on overall analysis of symptoms and signs,the cause,nature and location of the illness and the patient's physical condition according to the basic theories of traditional Chinese medicine, a variety of therapeutic mathods, clear effect, small side-effects and treating both the principal and the secondary aspects of a disease, its sympotoms and cause at the same time. So there are importance and broad useful prospect on researching and developing the nice,effective modern traditional Chinese medicine in curing the pneumonia (excess syndrome of the lung)[Methods] The project uses modern techological means in the experiment where the mouse has a fever by dried yeast. It includes:"Xingxuan BaiChengqi Capsule"researches protective effect infected with flu virus of fatal dose, and it has experiment of the feet metatarsal swelling of the mouse caused by carrageenin, still the experimental survey of antibacterial function of "Xingxuan BaiChengqi Capsule", influential experiment of cough model of guinea pig, experiment of resolving phlegm by "Xingxuan BaiChengqi Capsule"etc..The project studys and approaches pharmacodynamics effect of "Xingxuan BaiChengqi Capsule".[Results] 1,the experiment where where the mouse has a fever by dried shows "Xingxuan BaiChengqi Capsule"can clearly resist the fever response of mouse though t test; experiment group in comparison to control group p < 0.05, it indicates "Xingxuan BaiChengqi Capsule"has antipyretic function. the observation of infective animals caused by flu virus shows "Xingxuan BaiChengqi Capsule" can resuce death rate obviously of infective mouse caused by the fatal dose of flu virus.It demonstrates "Xingxuan BaiChengqi Capsule"has detoxifying function.2,"Xingxuan BaiChengqi Capsule"has clearly improvable function on mouth metatarsal swelling and can control inflammatory response.3,The observation of antibacterial experiment outside body shows "Xingxuan BaiChengqi Capsule"has clearly improvable function to Staphylococcus aureus,Diplococcus pneumoniae,influenza virus O-D variation,Escherichia coli,Pseudomonas pyocyanea with the concentration of 200mg/ml. It also shows "Xingxuan BaiChengqi Capsule"has antibacterial function.4,Experiment shows "Xingxuan BaiChengqi Capsule"can clearly expand cough incubation period of guinea pig with the dosage of 9g/kg,6g/kg, and can reduce cough times within unit time. It shows "Xingxuan BaiChengqi Capsule" has antibechic function.5,Experimental result of phenolsulfonphthalein test of mouse shows "Xingxuan BaiChengqi Capsule"can clearly strengthen phenolsulfonphthalein excretion amount in mouse windpipe with the dosage of 12g/kg,9g/kg,6g/kg and have clearly stimulative effect on resolving phlegm in mouse capillary veseel with the dosage of 12g/kg,9g/kg.[Conclusion] "Xingxuan BaiChengqi Capsule"has the function of clearing away heat and toxic material,anti-inflammation,anti-bacteria,relieving cough,resolving phlegm and place foundation for the development of new drug.