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Acute Cerebral Infarction Associated With Infection Serum Levels Of Tnf-a And Tcm Syndrome Related Clinical Research

Posted on:2008-03-23Degree:MasterType:Thesis
Country:ChinaCandidate:G L ZhuFull Text:PDF
GTID:2204360218456947Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
PuroseLacks the courage and uprightness brain stem to die harms humanity' sone of one kind of important diseases, according to the statistics, our country brain stem dead every year newly sends case of illnessapproximately 1.5-2 million, in some developed city brain stemstubbornly perishing rate achieved first, is the adult is most commonlethal and cripples one of reasons, has in the middle-aged person andold person case fatality rate place is only inferior saying of to thecancer. Our country brain stem dies the disease incidence rate assumes thetendency which advances year by year, its high disease incidence rate, the high mortality rate, high are sick and disabled rate has becomethreatens our country people health the most important disease.The brain stem dies the after inflammation to respond produces theinflammation medium lacks the important mechanism which the bloodcentral area and periphery the neuron damages. The tumor necrosisfactor is the brain lacks the bloodinflammation to respond produces the important inflammation medium, ithas been widely paid attention to in the brain stem dead patientneuron damage pathology process function.This topic plans to utilize the modern clinical epidemic ologyinvestigation method, through determination brain stem dead bloodserum in TNF-a, observes its dynamic change and the clinical significance, discusses it in to cause the brain to lack in the blooddamage the possible function mechanism, Through to lacks the courage and uprightness stem to die the acutetime partner to infect the patient and the brain stem dies non-infects patient's index of correlation comparison research, thoroughly discusses the infection to lack the influence which the courage anduprightness brain stem dies occurs, infects to lacks the courage anduprightness brain stem dead Chinese medicine card change theinfluence, to infects with lacks the courage and uprightness brainstem to refuse stubbornly the same Chinese medicine card evolutionrule to conduct the research. Thus, unifies the clinical epidemiology same Chinese medicine cardperiod of five days study, brings into line with the Chinese medicinecard period of five days under the modern medicine disease backgroundto study, and seeks the Chinese medicine card period of five daysstudy modern scientific foundation, for lacks the etiology and thedialectical minute which the courage and uprightness stem diesprovides the epidemiology basis, simultaneously provides the objectivetarget for the Chinese medicine card clinical diagnosis appraisalsystem, provides the new mentality for the Chinese medicine cardperiod of five days modernized research.MethodAll experimental group patients and the comparison group patients arethe patients which 2005-2006 year Hubei Province Chinese medicinehospital nerve internal medicine department is hospitalized. Theinfection group namely acute brain stem dead partner in the nearfuture will infect the patient: 32 examples, (male 21, female 9). Average age 62.30±9.25 year old. The comparison group the non-infection which is hospitalized for the same time lacks the courageand uprightness apoplexy patient 46 examples, (male 28, female 18). Average age 60.96±6.27. Completely receives examining after to be hospitalized next day earlymorning empty stomach 12h to extract elbow vein blood 3ml (to preventclotting withheparin sodium). Person TNF- the quota ELA reagent boxprovides by the Shanghai woods male science and technology industrylimited company, the TNF-examinationuses the double immune body tocontain filling the ABC-ELISA law, and carries on in a Wuhan hospitalexperiment center according to the medicine box instruction booklet. The complete data by (x±S) indicated that, two samples mean valuescomparison uses the T examination.Outcome and Conclusion(1) The acute time brain blocks partner acute infection group bloodserum TNF-a the content change to present the correlation (P<0.05).(2) The brain blocks the acute time patient Chinese medicine cardperiod of five days by the phlegm card primarily, accounts for 43%.(3) Qi deficiency the group does not have outstanding the difference with Qi deficiency the blood stasis group TNF-a level, but has outstanding the difference with other each group.This research indicated that, the acute infection patient blood TNF-acontent in the apoplexy acute time demonstrated obviously is high erthan without the infection group, and but gradually reduced along with the condition change for the better, confirmed TNF-a elevated pressesto send and to aggravate the brain stem dead condition, arose inprevious 2 weeks the infection is lacks the courage and uprightnessapoplexy the independence dangerous factor. Also this research for thoroughly carried on the cooperation of Chinese and Western medicine treatment apoplexy direction to provide afeasible pattern, to established the Chinese medicine card period offive days model, the Chinese medicine follows the card the research toprovide the theory and the practice basis.
Keywords/Search Tags:Cerebral infarction, Acute of infect, Nitric Oxide (NO), The Tumor Necrosis Factor-a(TNF-a)
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