The Shennong Xiangju Pharmacognosy And Chemical Composition

Dendranthema indicum var aromaticum is the dry capitulum ofcompositae plant Shen Nong fragrant chrysanthemum, which produces to theHubei Shennongjia area, distributes toward the sun open in elevation 2,000meter above spacious area, was discovered firstly and named by Mr. LiuQihong who works in Wuhan botanical research institute in 1982 inShennongjia, it was one kind of new resources plant, was a new variety,in Dendranthema compositae. It entirely had the special full-bodiedfragrance, the folk maked its flower and leaf which dried in the shadeas the sachet, heat-clearing drugs and the treatment in chronic hepatitis.Dendranthema indicum var aromaticum is the perennial herb. The plantis diminutive, entirely covered with the white fluff, the flower, leafor radical sparsely had the full-bodied fragrance. Stem, s base belt ispurple red; The leaf blade is much small and thick, the bottle-green, abovethe leaf, vein sticks up, under it small gland is hollow; The floweris small, yellow. This kind is approximate to the chrysanthemumindicum(D. indicum),the folk called it as the small mother chrysanthemum,comparing with the original variety, the main difference is: TheDendranthema indicum var aromaticum's leaf, the flower and so on havethe full-bodied special fragrance.The chemical analysis and the pharmacology experiment preliminaryresult indicated that: Dendranthema indicumvar aromaticum's flower, theleaf include alpha-thujone, beta-thujone and the borneo camphor andso on, a kind of terpene compound, but widely uses in industry, chemicalindustry, drink and medicine, has the certain development and useful value. Its flower, leaf can alleviates fever the disintoxicating effect, the folkuses it in treating the cold, the pharynx and larynx which is swollen andpainful, the eye which hot and so on, is one kind of the developmentmedicinal plant new resources which is worth studying. It used to preventand control the cold, the headache, bacillary-dysentery, and coronarydisease and hypertension, the Dendranthema indicum var aromaticum alsohas the function on sterilization, treating in disorders of the liver,dispersing the wind, lowering the blood pressure in the West Hubeimountainous area.At present, although Dendranthema indicum var aromaticum shapeingroups in the Shennongjia distribution area, has the quantity, butthe distribution scope is not big, and the resources is limited, weshould strengthen the protection, positively carrie on the artificialpropagation and the cultivation, reasonably develops the use. It can beused in treating the chronic hepatitis in the future.The thesis study on the Dendranthema indicum var aromaticum'spharmacognosy aspect research, has made a more detailed description onits raw material for medicine character and the microcharacteristic,provided some beneficial bases for further studying on the research andthe application of Dendranthema indicum var aromaticum. At the same time,we has carried on the separation and the purification to the Dendranthemaindicum var aromaticum in the chemical composition by using the silicagel column chromatograph; According to the physics and chemistry natureand the spectrum data (IR, MS, UV, ¹H-NMR, ¹³C-NMR, 2D-NMR), we carries onthe structure appraisal; has separated and appraised 5 compounds from theDendranthema indicum var aromaticum, respectively was:β-sitosterol, luteolin, daucosterol,apigenin-7-O-β-D-glucopyranoside, acacetin-7-O-β-D-glucopyranoside, and the last two compounds was reported firstly.The thesis used the highly effective liquid phasechromatography todetermine the content of Luteolin in the Dendranthema indicum vararomaticum, with system adaptability and methodology consideration,which has the advantage of systematism, allsidedness and characteristic.The method can be used to identify Dendranthema indicum var aromaticumand efficiently evaluate the quality of all sources of them. This methodcan be used to evaluate and control the quality of medicine wholly.