Non - Alcoholic Fatty Liver Disease Study On Characteristics Of TCM Syndromes Of Climate

1.ObjectiveThis dissertation maily concerned about the syndrome classification of clinical symptoms of non-alcoholic fatty liver disease including simple nonalcoholic fatty liver disease under the guidance of traditional Chinese medicine, and to determine the patients'distribution with the nomination and the disease type in order to support the diagnosis and treatment in the clinic practice . Clinical research, by reference guide TCM clinics of digestive disease, non-alcoholic fatty liver disease clinics Guide (revised in February 2006) and the clinical experience, developed clinical survey forms and collected cases. And the past history, tobacco and alcohol habits, medication history, weight, height, waist circumference, body mass index and the four Chinese medicine consultation, and other information were summarized. After the information on Statistical Analysis of entropy-reactorthese non-parametric rank and testing, Chi-square test and entropy-reactor of complex systems, the following conclusions were related.2. Contents and methodsThe thesis consists of three summaries of documents and a clinic research,and also includes some standards for diagnosis,clinic report table and the analysis results.The summaries consists of three parts .The first is about Modern Research Progress of non-alcoholic fatty liver disease .The second concerns about the research progress of TCM Syndrome of non-alcoholic fatty liver. The last tells the current treatment summary of non-alcoholic fatty liver with the method of the Traditional Chinese Medicine. And all these are intented to fully understand the results achieved and inadequate awareness of the research on Chinese and Western Medicine in non-alcoholic fatty liver disease and receive more information of the awareness of the disease so that the basis can be provided to draft out a case report table more scientificly.3.Results3.1 In the people of this research of non-alcoholic fatty liver disease, men accounted for 61.875%, while 38.125% of women, male to female ratio was 1.62:1, and men were more than women. And there is 21.25% of AST or ALT in patients with greater than 40 U/L. the course of 5 to 10 years is most.3.2 The average age of men and women compared with the samples of the two independent non-parametric test, suggested that the age of men and women in the overall sample with statistical significance (Z =- 5.493, P<0.001 bilateral), women were older, the ages of women were elder than men.3.3 The mergers of men and women such as obesity, hypertension, diabetes, hyperlipidemia,compared with the samples of the two independent non-parametric test suggested that there was no significant difference between men and women.3.4 In many related factors of non-alcoholic fatty liver disease,such as obesity, less exercise, work pressure and meat lover were main,and the most professionals were staff and cadres.3.5 The meaningful and positive symptoms and tongue veins of Non-alcoholic fatty liver disease were: dysphoria,flank and rib discomfort,bitter taste and dry throat,enjoying sighing,vexation, emotional depression, eructation, burnout and fatigue, chest distress; sallow complexion; light-reddish, slip, greasy, string, white, thin fur yellow, damp, less moss or no moss, red or dark red.3.6 Entropy-reactor of complex systems was used to classify 24 group syndrome, according to Chinese medicine theory into Qi deficiency, Qi stagnation, stagnated heat, stagnated fire, phlegm-damp, blood stasis, yin deficiency seven syndrome elements, and viscera involved liver, spleen and stomach.4.Conclusions4.1Male,age 40 to 59 years old, obesity, diabetes, hyperlipidemia,enjoying spicy and sweat, less exercise and work pressure may be risk factors of non-alcoholic fatty liver disease.4.2 Non-alcoholic fatty liver disease may be the important cause of the increase of AST, ALT.4.3 The syndrome types of Non-alcoholic fatty liver disease were mainly syndrome of liver-stomach heat , depression of the liver turning into heat,accumulation of phlegm-heat,liver depression and spleen deficience mixed with stagnated heat.5.Innovation5.1 Designed the Chinese medical questionnaire on the symptoms of non-alcoholic fatty liver disease.5.2 Entropy-reactor analysis of complex system and analysis of syndromes elements were used to receive the Chinese medical syndromes of non-alcoholic fatty liver disease.6. The shortcomings and solutions.6.1 Based on the development of literature, clinics and instructors guide the basis of the clinical development, the questionnaire was made but not carried out a questionnaire survey on expert advice. Suggest perfect the expert consensus,mixed with the reports and clinics with guidelines for the scientific development of the questionnaire.6.2 Small samples collected cases, limited patients crowd. Suggest a large sample, multi-center, random epidemiological investigation.6.3 Analysis of the survey results showed that two syndrome elements of phlegm and Qi deficiency not fully compatible with the clinical reports, propose that the idea of combination of disease and syndrome should be used in the future research of the syndrome of non-alcoholic fatty liver disease.