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Tcm Syndrome Differentiation Of Early Knee Osteoarthritis And Articular Cartilage Mri Effects Of Randomized Controlled Trials

Posted on:2009-10-23Degree:MasterType:Thesis
Country:ChinaCandidate:Z Q ZhangFull Text:PDF
GTID:2204360245957013Subject:Integrative Orthopedics
Abstract/Summary:PDF Full Text Request
Objective: To investigate the effects of the treatment of Chinese medicine on early knee osteoarthritis, observe the change and significance of articular cartilage MRI before and after the treatment.Methods: 60 cases were divided into two groups according to Doll's law, 32 cases in the test group (6 male and 26 female, the average age of 52.2 years ranging from 43 to 69 years) ,28 cases in the control group (5 male and 23 female, the average age of 54.4 years ranging from 42 to 66 years). The test group were given Chinese medicine by mouth and the control group were given celecoxib and the glucosamine hydrochloride by mouth for three months. MRI and HSS score were given respectively before treatment and in follow-up to observe articular cartilage changes of the loading area to evaluate the therapeutic effect.Results: 60 cases were all followed up for 13 to 17 months, with an average of 15.3 months. The total efficiency of MRI in the treatment group was 80% and the control group was 57.6%, significant difference was observed(t=5.07, P<0.05). The ISOA score of the test group after treatment was 0. 35, The average ISOA score of the test group after treatment was 0.35, and the control group was 3.68, significant difference was observed(t =6.94, P<0.05). t= 6.94, P <0.05, and the HSS score of the control group before and after treatment had no significant difference t = 2.07, P> 0.05.Conclusion: Chinese medicine can significantly reverse or inhibit the cartilage degeneration of early knee osteoarthritis and improve joint function. It had significant clinical effects.
Keywords/Search Tags:Chinese medicine, Knee osteoarthritis, Cartilage
PDF Full Text Request
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