Diabetic Foot Fasting Blood Glucose, Lipids And Glycosylated Hemoglobin Changes With Tcm Of The Study

Objective: To explore the correlation between syndrome patterns of traditional Chinese medicine and relative laboratory inspection items in 130 patients with diabetes foot (DF), and to explain its underlying formation mechanism, further more, to provide clinical treatment with convenient objective indicators.Methods: A unified clinical observation was made to collect clinical data of patients with DF, including symptoms and signs collected by the four methods of examination in TCM. Then all the patients were divided into four syndrome patterns by TCM differentiation. Meanwhile three laboratory inspection findings such as blood-fasting sugar level, blood-fat level and glycosylated hemoglobin level in the above patients were collected. Lastly, the correlation between syndrome patterns and laboratory inspection findings was analyzed.Results: Firstly, the study showed that the pattern of blood stagnation was particularly prevalent in 130 patients with DF. Secondly, the level of the blood-fasting sugar in all patients was higher than normal, especially in the patients with the pattern of toxic heat and Yin deficiency. The difference of the blood-fasting sugar level between the group with pattern of toxic heat and Yin deficiency and other groups was statistically significant (P<0.05). Thirdly, the glycosylated hemoglobin levels in patients with the pattern of channel stagnation by cold-damp were higher than patients with other three patterns, The difference between them was statistically significant (P<0.05). Lastly, the levels of triglyceride (TG) and low-density lipoprotein (LDL-C) in patients with the pattern of channel stagnation by cold-damp were higher than patients with other three patterns, The difference between them was statistically significant (P<0.05).Conclusion: Firstly, the dispositions and the changes of TCM patterns in patients with DF are peculiar. Secondly, if the level of blood-fasting sugar is far higher than normal, it is quit possible that the patient could be diagnosed with the pattern of toxic heat and Yin deficiency. Thirdly, the level of glycosylated hemoglobin can be used as an indicator for toxic heat and Yin deficiency pattern in DF differentiation. Lastly, the levels of triglyceride and low density lipoprotein-cholesterol can be used as two differentiation indicators in the pattern of channel stagnation by cold-damp.