Compound Chinese Medicine Extract Preparations On Hepatic Free Radical Metabolism In The Different Functional Status Of The Trained Rats

1 Objective:Study the compound prescribe Chinese herbal medicine withdraw the thing product and sport train to be placed in dissimilarity the function condition descend the big rat liver free radicals metabolism of influence, further understanding the Chinese herbal medicine oxidize in the anti-defer sport tired, to promote the machine body instauration the function of with etc., is science of instruction sport train and all the people workout provide certain of theories basis.2 Method:8 the week-age wistar the big rat is 200s, weight about 200 g, random is divided into 4 sets of: S(peaceful set),E(the medicine set),T(the sport set),F.(sport add the medicine set)8 week the swimming train behind each according to peaceful appearance, fixed amount sport 1 h, the dint instant, the dint instauration 12 h, the dint instauration the 24 h be divided into 5 second set, correspond time break a head to sentence to death; Take the liver treat to measure C two MDA, the revivification type GSH content with sweet valley, the super oxide turn SOD, the valley the sweet lead oxide GSH-PX, total anti- to oxidize the ability T-AOC activity. All data use SPSS17.0 covariance software package processing, beg average number, number, Sigma, and carry on independence the sample T examination, show the standard as the P<0.05, pole show standard for the P<0.001.3 Results:3.1 Peaceful appearance In quite state, The MDA content, the E set show low in S set(the P<0.05), the F set show low in the S set and the T set(the P<0.05), the F set is low in the E set, but didn't show the difference;(P>0.05)The SOD and the GSH-PX activity, the T set show high in S set(the P<0.05), E set the pole show high in S set(the P<0.001), F set the pole show high in the S set and the T set(the P<0.001),show high in E set;(the P<0.05)The GSH content, the T set and E set all show high in S set(the P<0.05), F set the pole show high in the S set(the P<0.001),show high in T set(the P<0.05), the F set is high in the E set, but didn't show the difference;(P>0.05)The T-AOC activity, the T set and E set all show high in S set(the P<0.05), F set the pole show high in the S set(the P<0.001),show high in the T set and the E set.(the P<0.05)3.2 At the immediate ends of exhaustive exercise, in the tissue of muscle,The MDA content, the T set and E set show in S set(the P<0.05), F set the pole show low in the S set(the P< 0.001),show low in T set(the P<0.05), the F set is low in the E set, but didn't show the difference;(P>0.05)The SOD and the GSH-PX activity, E set the pole show high in S set(the P< 0.001), F set the pole show high in the S set and the T set(the P<0.001),show high in E set(the P <0.05), the T set is high in the S set, but didn't show the difference;(P>0.05)The GSH content, the T set is high in the S set, but the difference do not show (P>0.05), the E set show high in S set(the P<0.05), the F set show high in the S set and the T set;(the P<0.05)The T-AOC activity, the F set show high in the S set and the T set(the P<0.05), each set of rest do not show the difference.(P>0.05)3.3 The MDA content, E set the pole show low in S set(the P<0.001), F set the pole show low in the S set and the T set(the P<0.001),show low in E set(the P<0.05), the T set is high in the S set, but didn't show the difference(the P>0.05).The SOD activity, the T set and E set pole show high in S set(the P<0.001), F set the pole show.high in other 3;(the P<0.001)The GSH-PX activity, the T set show high in S set(the P<0.05), the E set and F set pole show high in S set(the P<0.001), F set the pole show high in the T set and the E set;(the P<0.001).The GSH content, T,E,F3 set the pole show high in S set(the P<0.001), the F set show the high T set and E set;(the P<0.05)The T-AOC activity, the T set show high in S set(the P<0.05), the E set and F set pole show high in S set(the P<0.001), the F set show high in T set(the P<0.05), the F set is high in the E set, but didn't show the difference(P>0.05).3.4 The instauration is 12 hours after the dint The MDA content, the T set show low in S set(the P<0.05), the E set and F set pole show low in S set(the P<0.001), the F set show low in T set(the P<0.05), the F set is low in the E set, but didn't show the difference;(P>0.05)The SOD activity, T,E,F 3 sets of pole show high in S set(the P<0.001), F set the pole show high in the T set(the P<0.001),show high in E set;(the P<0.05)The GSH-PX activity, the T set show high in S set(the P<0.05), the E set and F set pole show high in S set(the P<0.001), F set the pole show high in the T set(the P<0.05),show high in E set. The GSH content, the T set and E set show high in S set(P<0.05), F set the pole show a high S set(P<0.001) of and show high in T set(P< 0.05), the F set is high in the E set, but didn't show the difference;(P>0.05)The T-AOC activity, the T set and E set show high in S set(the P<0.05), F set the pole show high in the S set and the T set(the P<0.001),show high in E set(the P<0.05).3.5 The instauration is 24 hours after the dint The MDA content, the E set show low in S set(the P<0.05), the F set show low in the S set and the T set(the P<0.05), the F set is low in the E set, but didn't show the difference;(the P>0.05)The SOD and the GSH-PX activity, the T set show high in S set(the P<0.05), E set the pole show high in S set(the P<0.001), F set the pole show high in the S set and the T set(the P<0.001),show high in E set;(the P<0.05)The GSH content, the T set and E set show high in S set(the P<0.05), F set the pole show high in the S set(the P<0.001),show high in T set(the P<0.05), the F set is high in the E set, but didn't show the difference (P>0.05).The T-AOC activity, the T set and E set all show high in S set(the P<0.05), F set the pole show high in the S set(the P<0.001),show high in the T set and the E set(the P<0.05). 4 Conclusion4.1 The swimming of 8 weeks train and can lower the MDA content in the big rat liver organization, exaltation SOD,GSH-PX,T-AOC of activity and GSH content, strengthen the machine body dissimilarity the function appearance under of the anti- oxidize an ability.4.2 The compound prescribe Chinese herbal medicine withdraw the thing product" can lower the dissimilarity appearance to descend the big rat liver organization MDA content availably, the activity of the SOD, GSH-PX,T-AOC and the content of the GSH in the exaltation big rat liver organization, speed the clearance of the free radicals, exaltation the machine body at dissimilarity the function appearance under of the anti- oxidize level.4.3 The compound prescribe Chinese herbal medicine withdraw the thing product" is in conjunction with sport to train to descend the activity that the big rat liver organization variety anti- oxidize to the exaltation dissimilarity appearance the medicine set than the pure and pure sport the set have more obvious of result.