| Time medicine is a newly-rising and popular branch of modern medicine. Characteristics of time medicine are a production which combines modern time medicine with TCM, and "chrono-medication" is an important part of Characteristics of time medicine. The past physicians have gone through thousands of years for accumulation and development, creating a set of "Correspondence between Man and Nature,"and the theory of "chrono-medication". To realize the academic thoughts and the drug experiences related to "chrono-medication" thoroughly and systematically, this article collected the ancient and related references and analyzed on "chrono-medication" ideas and methods, combined with modern time medicine of research.In other words, it is a preliminary study of the "chrono-medication" mechanism, the diseased entities which are favorable for "chrono-medication", "chrono-medication" method of types and laws, "chrono-medication" clinical significance, and so on. The conclusions are as the following:IThe academic thoughts of "chrono-medication":The academic thought of "chrono-medication" originated in the Warring States philosophy. "Nei Jing" established "chrono-medication" principle and "zabzabinglun" proposed "chrono-medication" approaches and herbs, making "chrono-medication" academic thought mature. The "chrono-medication" academic thinking enriched the development to the full in Jin and Yuan period. In Ming and Qing Dynasty, "chrono-medication" academic thinking came to perfect. Nowadays the literature regarding the "chrono-medication" of the discourse modernized "chrono-medication" thought.2The mechanism of "chrono-medication":It should adjust to the law between Ying and Yang in human body, to comply with the law of the Viscera; the rules "When ying and wei qi" performed in the human body; to the law of human Qi change and to take advantage of the human body Synchronous rhythm with the nature of time and the medicinal properties of potency drug for prescribing to improve clinical efficacy. 3"chrono-medication" the law for the disease:For example, it includes the seasonal onset of disease, the disease situation which is different between daylight and night, different disease location and the situation of the patient. These diseases have the strong time property so it can choose food service to improve drug efficacy.4The categories of "chrono-medication" and its rules:4.1To medicate according to population fluctuation of Yin and Yang, the Viscera and four seasons:It follows "Nei Jing", "protecting yang in spring and summer, protecting yin in autumn and winter"," the theory includes that liver is primary in spring, heart is primary in summer, spleen is primary in long summer, lung is primary in fall and kidney is primary in winter". To medicate according to the various situations and time, It can reach the best effect with the time and seasons.4.2Follow the seasonal factors in medication:Select the medicine according to the seasons. For instance, the exogenous disease should pungent-cool dispersion in spring and summer and relieved exterior in fall and winter. The aspect of deficiency disease in spring and summer just past soft drug use wish away and in autumn and winter should be far past just soft. And be responsive to changes in selection down four seasons the methods of sweat, spit and excretion.4.3According to the law of moon on medication:The typical instance to demonstrate the law of moon in human body is the rising and falling level of Qi and blood in women's bodies. The Optional medication can be dated with reference to the changes in the actual situation and Symptom reinforcing and reducing the time to master.4.4Follow the Circadian Rhythm medication:We can choose the medicine reinforcing Kidney, Invigorating Yang, including vomiting and perspiration. It is appropriate to use benefiting Qi and raising Yang and relieving exterior syndrome by diaphoresis before noon; it is appropriate to insecticide, purgative in the afternoon; it is appropriate to supplement Yin blood at night; to tranquilize spirit and relieve convulsion before we go to bed. Following the circadian law of human body to be on medication to strengthen the medicine is the best synergistic effect.4.5According to the disease location and the disease potential drug: "Plain Questionsâ–¡Chriex" mentioned that "sick while in the far Road, odor, and then, they had to eat and no more of their systems also." As a result, the effects of drugs depend on when to take in the food and thus force the effects of the drug to disease location. For instance, the disease is located in the mediastinoscopy, blood, bone marrow, external or internal part. Disease developing upwards or downwards likewise differ in its time to take the medicine. To co-Almost "meets with the disease situation and the interests of the government guidance," "correction of the situation and restore almost sick of the Rule also" of a concrete applications.4.6According to the rise and fall the Qi of the medication:Adjust to the state of the seasonal air-choose herbal Xingan divergence, Suan Ku Chung vent, salty Chung vent, lights, the features associated with seepage discharge, so that the drug simultaneously functions with the Qi and thereby enhances the ability of the medicine.4.7Medicate according to the properties of drug:Drugs has the properties of ownership of twelve channels, while the twelve channels gas flow Note has time law. Consequently, the best time for use of drug which belong to one of twelve channels is corresponding with the channel hour.5Clinical significance of "chrono-medication":It is beneficial to the human body with the natural biological rhythm to improve clinical efficacy, to induce disorders of rhythm backing to normal and to reduce and prevent harmful drug reactions. The core lies in the human body of the natural physiological and pathological changes showing synchronous changes of movement and the choice of drugs. Therefore, the drug law must follow rise and fall of the natural rhythm and the medicine properties. |
