| Purpose: To observe the Lianxin particle for the treatment Coronary Heart Disease Premature ventricular contractions (Breakdown of normal Physiological coordination between the heart and the kidney) in clinical efficacy and safety。Method:We selected in accordance with 73 cases observed cases under the inclusion criteria,73 cases were randomly divided into the experimental group and control group. To rhythm control drugs rather to observe the convergence of clinical symptoms in patients with heart particles on the dynamic electrocardiogram (Holter) recording changes in the number of PVCs and blood routine, urine routine, liver function, kidney function and other safety indicators. Test group: oral Lianxin particle 1 bag each time, 3 times a day for 4 weeks; control group: heart rate Tablets simulated dose (100mg / tablet), 2 tablets each time, 3 times a day for 4 weeks. Finally SPSS15.0 statistical software for data analysis, with Ridit level data analysis, count data using chi-square tests, t-test measurement data, the study results.Results:1. Efficacy Evaluation: control premature: the total effective rate was 59.46%, total effective rate of the control group 27.78%, the two groups were statistically significant difference (P <0.05); Comparison of treatment the number of premature ventricular contractions group and the control group there were significant differences (P <0.05). Description convergence heart particles and the number of matrine has reduced the role of premature beats, but the convergence center particles than the control group. In improving clinical symptoms: the total effective rate was 94.60%, total effective rate in control group 55.56%, clinical symptoms between the two groups was statistically significant difference (P <0.05). Convergence Granule group than the control group.2. Safety Evaluation: During the experiment, found no adverse reactions, Lianxin particle has good security.Conclusion:1. Lianxin particles can significantly reduce the number of heart ventricular coronary heart disease (heart and kidney do not pay license) with PVCs occurred;2. Lianxin particles can effectively improve cardiac ventricular premature coronary heart disease (heart and kidney do not pay license) symptoms in patients with Chinese medicine;3. Lianxin particles treated Coronary Heart Disease Premature ventricular contractions has good security. |
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