Shan Fu Fang And Swimming Exercise On High-fat Diet In Rats Body Weight And Some Serum Markers

Objective To investigate the effect of compound recipe CHT combined with 90 minutes swimming exercise on connected serum guideline and physiol- ogical guideline to diet-induced hypercholesteremia rats.Method 50 Male SD rats were selected and divided into 5 groups :control group,hyperlipidic diet contrast group(Hf), hyperlipidic diet with 90 mintues exercise group(HfEx), hyperlipidic diet with compound recipe CHT group(HfTm), hyperlipidic diet with 90 mintues exercise and compound recipe CHT group(HfExTm).All groups are fed with hyperlipidic diet except control group to establish obesity rats modle.The rats of HfEx and HfExTm groups swam for 90 minutes without weight every day during 7 weeks,6 daysevery week.The rats of HfTm and HfExTm groups are fed with compound recipe CHT every day during 7 weeks,6 days every week as standard 3.3g/kg.bw every day.we get the level 3.3g/kg.bw.control,Hf,HfEx groups are fed with distillation water as the same level.After seven weeks of treatment ,the rats were killed 24 hours after the last exercise.After weighing ,we can take out the blood seum of the rats and determine the amount of TC,TG,HDL-C and insulin.just after taking out blood,we begin anatomizing,weighting epididymal fat pad and kidney fat pad.Result Use SPSS 11.5 statistics software to carry on the statistical analysis.After comparing,the auther finds Lee`s index of the rats in Hf group increases remarkably(P<0.05)compared with the rats of control group.Next results are all compared with Hf group.The body weight of the rats in HfTm group and HfExTm group descends significantly(P<0.01). The epididymal fat pad and kidney fat pad of the rats in HfExTm group descends significantly(P<0.01).HfTm group have an descending effect on TC(P<0.05), HfEx and HfExTm groups have obvious descending effect on TC(P<0.01).HfExTm have an obvious descending effect on TG(P<0.01).HfTm,HfExTm and HfEx groups have effect on HDL-C(P<0.05).Conclusion Fom the results,we can get the following conclusion.(1)Tt is successful to establish obesity rats model just using hyperlipidic diet. (2)Compound recipe CHT can descend the weight of rats which is fed with hyperlipidic diet.it can prevent the ats from weighting.(3)Compound recipe CHT has coordination effect with 90 minutes swimming exerciseing on des- cending the weight of epididymal fat pad and kidney fat pad,so it can descend fat.(4)Compound recipe CHT can descend the level of serum TC,TG, Compound recipe CHT has the tendency to increase the level of serum HDL-C.