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Analysis Of Clinical Cases Of 90 Patients With Buccal Squamous Cell Carcinoma

Posted on:2011-08-12Degree:MasterType:Thesis
Country:ChinaCandidate:X LiuFull Text:PDF
GTID:2214330335491674Subject:Oral and clinical medicine
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Objective:The author report and analysis 90 patients with buccal squamous cell carcinoma treated in the Second Xiangya Hospital form january of 2006 to 2010 january.From their clinical data and postoperative information,the incidence of buccal squamous cell carcinoma, surgery After the reconstruction, and prognosis of data collection and collation, analysis on the buccal squamous cell carcinoma prognostic factors, of appropriate treatment for the comprehensive evaluation of the treatment and prognosis of clinical evidence.Methods:90 patients were diagnosed as cases of buccal cancer in Second Xiangya Hospital of Central South University from 2005 to 2010 and pathological diagnosis of clinical data analysis, and related these patients and postoperative adjuvant therapy (chemotherapy) and functional recovery and quality of life of the current return visit, on the above information to be processed and statistically analyzed.Results:1.The incidence and the ratio and composition of the buccal squamous cell carcinoma90 patients with buccal squamous cell carcinoma patients, the number of 18 cases lost. Return visit rate of 80.0%, Return visit to the longest 63 months, minimum 3 months.65 of 90 patients in the male, female 25, male to female ratio is:2.6:1. Youngest patients is 31 years old. Maximum is 89-year-old. Average age:58.2 years. Diagnosed at the age:40-70.Pathological type of which was well-differentiated squamous cell carcinoma were:76 cases, accounting for 84.4%. Moderately differentiated squamous cell carcinoma:13 cases, accounting for 14.5%. Poorly differentiated:1 case,1.1%.2.The treatment of buccal squamous cell carcinoma90 patients with buccal squamous cell carcinoma in the original tumor resection and neck dissection in patients over the same period:82 cases, including:radical neck dissection in 13 cases, accounting for 15.9%. Implementation of functional neck dissection were:59 cases, accounting for 72.0%. Implementation of the shoulder dissections in 10 cases, accounting for 12.1%. Implementation of the extended resection alone, without making neck dissection in 8 cases, accounting for 8.9%. Border in all patients with negative margin rate:100%.Lymph node metastasis:82 patients with buccal squamous cell carcinoma surgery, according to the clinical TNM classification UICC 2002 years, divided into N categories:No:52 cases, accounting for 63.4%. N1:11 cases, accounting for 13.4%, N2:19 cases, accounting for 23.2%. Lymph node metastasis rate:36.6%(30/82)3. reconstruction of Cheek soft tissue defectThe reconstruction of buccal cancer patients:Anterolateral thigh myocutaneous flap:54 (all survived) forearm flap:24 (one case of partial necrosis). Pectoralis major muscle flap:5 (1 case of necrosis). Latissimus dorsi flap 1. Other types of valve 6:4 nasolabial fold flap, buccal fat pad Debate+artificial membrane 3. Assembly success 97.9%, flap 80, the total success rate:98.7%4. Prognosis90 patients with buccal squamous cell carcinoma:3 year survival rate was 72%. 5-year survival rate was 64%.Buccal squamous cell carcinoma prognosis factors 1, TNM classification:the prognosis of patients with buccal cancer, T stage and N stage increased and decreased 2, clinical stage:advanced buccal carcinoma, patients with worse prognosis than early. 3, Whether barrier through the cheek muscle, is an important prognostic indicator of poor prognosis through the cheek muscle.4, pathological types:highly differentiated better outcome in the differentiation of those.5.Conclusion1.90 patients with buccal squamous cell carcinoma, sex ratio:2.6:1. Diagnosed at the age:40-70.2.82 patients with buccal squamous cell carcinoma lymph node metastasis rate: 36.6%(30/82).3.90 patients with buccal squamous cell carcinoma survival rate in 2010 was 72%,5-year survival rate was 64%4.With buccal cancer prognostic indicators include:cheek muscle tumor invasion. T stage, lymph node metastasis, clinical stage, pathological type.
Keywords/Search Tags:buccal squamous cell carcinoma, en-bloc resection, repair, survival, recurrence and prognosis
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