Clinical Research Of Xing Qi Run Chang Fa On Treating The Irritable Bowel Syndrome With Constipation

Objectives:To observe the clinical effects in treating the Irritable bowel syndrome with constipation caused by Qi stagnation, intestinal dryness by the method of Xing Qi Run Chang.Methods:This research was based on 60 cases of outpatients with Qi stagnation, intestinal dryness and were randomly divided into two groups. One group was the treatment group,30 patients of which were treated with Xing Qi Run Chang Fang. The other group was the control group, with 30 patients being treated with Macrogol 4000 powder for oral solution, but 1 case fell off. These patients all met the diagnosis criterion. Both groups were treated for four weeks. The changes of clinical symptoms before and after treatment and after one month of untreatment were detected respectively to evaluate the therapeutic effects, safety inspection and long-term clinical efficacy.Results:1. In the treatment group,9 cases recovered and 11 cases significantly improved,8 cases improved,2 ineffectual cases. The total effective rate in the treatment group is 93.33%.In the control group 3 cases recovered and 8 cases significantly improved,10 cases improved,8 ineffectual cases. The total effective rate in the control group is 70.00%. There is a significant difference in the total effective rate between the treatment group and control guoup in the statistics (P=0.009<0.01).The effective rate from the treatment group is clearly superior.2. The efficacy of the treatment group is improved obviously in abdominal distension, abdominal pain, defecation state, stool frequency, defecate impeded, unsatisfied feeling of defecation, mucous stool and dry mouth(P<0.05), and the control group, except dry mouth, the rest are obviously improve symptoms (P<0.05); The degree of improvement about the treatment group is better than the control group in abdominal pain, defecation state, stool frequency and dry mouth (P<0.05), and is equivalent to the control group in abdominal distension, defecate impeded, unsatisfied feeling of defecation and mucous stool (P>0.05)3. The time of Xing Qi Run Chang Fa on alleviating the abdominal distension, abdominal pain unsatisfied feeling of defecation is faster than Macrogol 4000 powder for oral solution(P<0. 05). But is same in defecation state, stool frequency, defecate impeded and mucous stool (P>0.05)4. In the observation, the two groups were not found significant side effects. 5. After one month of untreatment, the long-term clinical efficacy of the treatment group is better than the control group's(P<0.01).Conclusions:Xing Qi Run Chang Fa has the significant, safe and good long-term clinical efficacy in the treating the irritable bowel syndrome with constipation caused by Qi stagnation, intestinal dryness.