Relationship Between Levels Of Serum Fgl2 And ACS

Objective:To check out the peripheral serum levels of fgl2 in patients with acute coronary syndrome (ACS), analyze its relationship with the ACS and the severity of coronary artery lesions. besides, to approach its diagnostic value in acute coronary syndrome.Methods:Seventy-three patients with coronary heart disease and 15 persons without coronary heart disease were studied. Among patients with coronary heart disease,there were 21 patients with acute myocardial infarction(AMI),32 patients with unstable angina pectoris(UAP),20 patients with stable angina pectods(SAP). All patients with coronary heart disease inspected by coronary angiography were divided into three vessel lesions group, two vessel lesions group and single vessel lesion group by the lesions severity of coronary artery. The serum concentrations of soluble fgl2 were measured in all patients with coronary heart disease and controls. The extent of coronary arteriostenosis was evaluated with Gensini Scores. The levels of serum fgl2 and the extent of coronary arteriostenosis were analyzed.Results:Serum fgl2 levels were remarkably higher in patients with AMI group and UAP group than those in SAP and NCHD group(p<O.05), there was no significant difference in the level of fgl2 between SA group and NCHD group(p>O.05). Gensini Scores were no significant difference in patients with different types of coronary heart disease (p>0.05).Conclusion:Level of serum fgl2 increased in patients with ACS and it may be in coronary heart especially acute coronary syndromes as one of predictive value coronary Micro thrombosis acute-phase protein.Levels of serum fgl2 had no relation with the extent of coronary arteriostenosis among patients with coronary heart disease.