Clinical In Vestigation Of The Major Factors Of Effecting Epidural Anesthesia

Objective:To apply the same quality and the different concentration or volume dose lidocaine hydrochloride, comparing the change of sensory block and degree of motor block, discussed the major factors of effecting epidural anesthesia.Methods:Selecting epidural anesthesia in patients undergoing elective knee joint surgery under the 40 cases, aged 20 to 60 years of age, 21 males,19 females, ASAⅠ-Ⅱ, all cases were punctured at lumbar 2-3 spinal inter space. Basisde on Random numbers table they were randomly divided into two groups:1% lidocaine hydrochloride 30ml(n=20), or 2% lidocaine hydrochloride 15ml(n=20). After epitural anaesthesia was completed, injecting lidocaine hydrochloride 60 milligram, no adverse reactions injecting the remaining amount after 5 minute. The spread of the sensory block to pinprick and the dgree of motor block(modified Bromage scale)were measured at 15,30 and 40 minute after injection. Each blood pressure (BP), mean arterial blood pressure(MAP) and heart rate (HR) were were recorded at immediately transferred to operating room, after administration 15 minute,30 minute and 45 minute. The does of ephedrine hydrochloride were recorded.Results:There were no significant differences in the blood pressure and heart rate. There were no significant differences in the progression of analgesia and motor block were observed at any time between 1%and 2%lidocaine hydrochloride. The does of ephedrine hydrochloride were no significant difference in both groups.Conclusions:Apply the same quality and the different concentration or volume dose lidocaine hydrochloride could emerge the same block effection, deciding the major factors of epidural anesthesia was the number of molecules.