| purpose:Research the MoCA scale application in screening ischemic MCI, evaluate MoCA scale screening mild cognitive impairment value; Observe vascular mild cognitive dysfunction epidemiological characteristics, imaging features, and neuropsychological features.Method:Choose the patients in acupuncture and rehabilitation hospital of jiangsu province from September 2010 to 2011 February, and the nerve of ischemic cerebrovascular disease hospital physician (such as cerebral blood deficiency. TIA, cerebral infarction) and with cognitive impairment complaint with CDR screening patients, including dementia patients, (CDR=0.5), a total of 67); Garnish with MoCA screening out of 19, and cognitive 1.7-fold mild cognitive disabilities 48 cases; The screening out of MoCA poste MMSE evaluation, patients with MCI detection,25 cases score abnormalities,23 cases of patients with MCI failed to detected; The screening out of MoCA cognitiely normal group were also poste MMSE check properly. MoCA screening for a mild cognitive disabilities case group, cognitive normal for control; Record the cognitive areas to score.Results:MoCA significantly associated with MMSE score points (Rs=0.963, P< 0.01). and the detection rate of MoCA 71.6% than MMSE detection rate 37.3%(P< 0.001). MoCA detected cognitive normal individual MMSE evaluation also is normal; And MoCA detected mild cognitive impairment individual, can only be detected which MMSE remaining 52.1% of 47.9% failed to detected,(P<0.01). Cases of gender comparison group and the control group (P>0.05 no difference). Cases group and control group age is a statistically significant (P< 0.05), age is cognitive function decline important factors. In case group total MoCA hypertension group below normal bp group (P<0.05). In both groups diabetes, coronary heart disease, hyperlipidemia, compared the sick number was not statistically significant (P>0.05). In MCI group (CPT) a recurrence of total score below group MMSE and MoCA starting group (P<0.05). With multiple lesions group MMSE and MoCA average composite score below no lesions group and a single lesion group (P<0.05). MCI group scores are lower than the cognitive areas to cognitiely normal group, executive function and visual spatial ability, attention, language ability, memory, abstract thinking for the (P<0.05), naming and directional power relative retention. Cerebral infarction part of the frontal and temporal lobes, thalamus. brain white matter loose two groups of comparisons are statistically significant (P< 0.05).Conclusion:MoCA score significantly associated with MMSE score high sensitivity. MoCA detection, high, can discover what MMSE missing mild cognitive impairment patients; Age, hypertension, ischaemic stroke of recurring, intracranial ischemic lesions of the amount, gathered based disease related and cognitive function; Ischemic cerebrovascular disease occurred after mild cognitive dysfunction in executive function, visual spatial ability, attention, language ability, memory, abstract thinking, obviously affected cognitive areas such as directional force, naming basic retained. Frontal and temporal lobes, thalamus infarction and cerebral white matter with ischemic cerebrovascular disease osteoporosis after about cognitie decline. |