A Study On The Correlation Between Glycosylated Hemoglobina1c And Of Sudden Sensorineural Hearing Loss

Objective: This paper compares hemoglobin A1c levels≥6.5℅ and <6.5℅ two groups of patients with sudden sensorineural hearing loss clinical data, hearing loss characteristics and efficacy of hemoglobin A1c and the relationship between sudden deafness, and glycated hemoglobin A1c examination in patients with sudden deafness significance.Methods:①Clinical data: From January 2009 to December 2010 in the Department of Otolaryngology, Second Affiliated Hospital of Dalian Medical University, course of hospitalization within 1 month in patients with sudden sensorineural hearing loss.②Grouping method: the diagnosis of all patients with sudden sensorineural hearing loss, 2 days after admission check fasting glycosylated hemoglobin A1c. Glycated hemoglobin A1c≥6.5℅ of patients into the trial group, <6.5℅ of patients into the control group. Age of the patients due to the experimental group were≥38 years of age, to prevent the interference of the age factor, the age <38 years of age and hemoglobin A1c <6.5℅ patients excluded. Test group of 59 patients, a total of 70 ears. Including 25 males and 34 females. 30 cases of left ear, right ear in 26 cases, incidence of ears while in 7 cases (total 14 ears). 58 patients in control group, a total of 61 ears. Including 22 males and 36 females. 26 cases the left ear, right ear in 29 cases, incidence of ears while 3 patients (total 6 ears).③Diagnosis is based on: for all study subjects pure tone threshold check (PTA), distortion product otoacoustic emission (DPOAE), auditory brainstem response (ABR), CT examination of internal auditory canal, according to the patients medical history and examination excluded retrocochlear lesions above , a clear diagnosis. Audiological test results were compared characteristics.④All patients were currently recognized as the comprehensive treatment. Attention to rest, appropriate sedation, aggressive treatment of related diseases, such as hypertension, hyperthyroidism and so on .Use of drugs to improve circulation, nutrition, drugs, and to neural lipid anticoagulant treatment. At the same time and support given to glucocorticoid hyperbaric oxygen therapy. In which severe and very severe sensorineural hearing loss patients are also given Batroxobin. 10 days for a course of treatment, after treatment by a review of the pure tone threshold check, according to the pure tone hearing thresholds before and after treatment Analysis returns inspection results.⑤Statistical Methods: SPSS17.0 package, the two groups of patients according to gender, age, hearing-impaired ear, listening graphics, level of hearing loss, hearing recovery after treatment, such as numerical variables were statistically described.Results: (1) Sex between the two groups before treatment compared with incidence of hearing loss ear was no significant difference. Ear disease in the test group the proportion of patients than the control group, but the difference was not statistically significant. (2) Before treatment level of hearing loss significantly (X~2 = 22.599, P <0.01), the experimental group the proportion of patients with moderate hearing loss up to the control group, the proportion of patients with mild hearing loss the most. Graphic classification hearing in accordance with the two groups are the decline in high-frequency hearing loss in heavier type of audiogram up, no significant difference between the two groups (X~2 = 4.265, P> 0.05). Loss of hearing threshold at each frequency compared to the situation significantly (P <0.05), which 8KHz difference between two groups was significant (F = 1.230, P <0.01) (3) Compared two groups after treatment was significantly statistically significant (X2 = 26.549, P <0.01). (4) After treatment, the situation 4KHz and 8KHz improvement of hearing was no significant difference (4KHz: F = 0.000, P> 0.05; 8KHz: F = 0.809, P> 0.05).Conclutions:1.HbA1c in patients with sudden sensorineural hearing loss ear hearing loss has nothing to do with the patients gender.2.HbA1c rise will increase the degree of hearing loss, sudden sensorineural hearing loss, the effect of sudden sensorineural hearing loss.3.High-frequency hearing recovery and the degree of initial hearing loss, has nothing to do with the HbA1c level.4. Given to patients with sudden deafness glycated hemoglobin test can help early diagnosis of diabetes, and blood glucose in patients with diabetes to understand the situation. Can also serve as an estimate of sudden deafness prognosis of, for a comprehensive clinical treatment to take timely measures, has a positive significance.