| Objective: Diabetes is one kind of metabolic diseases with highblood glucose for key features, and Cerebral Infarction is one of seriouscomplications of diabetes. In recent years, with the improvement ofpeople's living standards and the reducing of physical labor and exercise,the incidence of diabetes mellitus with cerebral infarction(DMCI) ishigher and higher. In the last twenty years, Monitoring data shows thatthe stroke death annual rate is8.7. In clinical, It becomes more importantto diagnose and treat by typing. Cerebral infarction belongs to stroke inthe category of traditional Chinese medicine (TCM), and there is richclinical and treatment experience of treatment based on syndromedifferentiation. In order to give full play to the advantage of combina-tion of Chinese traditional and western medicine, we divided the DACIpatients who were diagnosed clearly by Western medicine into differentclinical classifications, and contrast with TCM syndrome differentiation.Discuss the relation between syndrome differentiation of TCM andTyping of type2diabetes mellitus combined with acute cerebralinfarction(DACI), we expect to provide a new research idea and methodfor TCM syndrome differentiation of DACI,so as to guide thecombining traditional Chinese and Western medicine treatment andenhance the curative effect, reduce disability.Methods: The88cases of DACI are selected from hospitalizedpatients in the Second Hospital of Hebei Medicine University, and allthe selected cases meet the diagnostic criteria of cerebral infarction ofChina acute ischemic stroke diagnosis and treatment guidelines made in2010and the type2diabetes mellitus (DM) diagnosis standard made in1999of WHO, We divided it into three types according to clinicalaccessing standard of neurological function in stroke: mild, moderate and severe. The cases were selected for syndrome elementsdifferentiation by using the "syndrome differentiation grain scale" inSyndrome factor dialectical studies created by Zhu Wenfeng. Choosegreat clinical significance syndrome according to different classification,make statistics and analysis,discuss the correlation between SyndromeDifferentiation of TCM with Typing of Type2Diabetes with acuteCerebral Infarction(DACI).Results:1Symptom Distribution of type2DACIMild typing symptom distribution of type2DACI: hemiplegia,string pulse, dizzy, rapid and thin pulse, inhibited speech, thirsty, drystool/constipation, yellow coating, little coating/withouting, slipperypulse.Moderate typing symptom distribution of type2DACI: hemiplegia,inhibited speech, string pulse, dry stool/constipation, dizzy, thirsty,dark-red tongue, short breath or low voice, deviation of tongue, sharpcough due to drinking.Severe typing symptom distribution of type2DACI: string pulse,hemiplegia, inhibited speech, dry stool/constipation, dark-red tongue,wandering mind, deviation of tongue, sharp cough due to drinking, morethan normal weight, thirsty or coughing2Syndrome elements distribution of type2DACI2.1Syndrome elements of disease nature distribution of type2DACISyndrome elements of disease nature which closely tied to type2DACI are: phlegm and damp, Yin deficiency, internal wind, Yangexcess, blood-insufficiency,fire or fever,Qi deficiency, blood stasis,Bisyndrome.Mild typing are mainly composed by Yin deficiency andphlegm&damp.Moderate typing are mainly composed by Yin deficiency,phlegm&damp and internal wind.Severe typing are mainly composed byYin deficiency, phlegm&damp,internal wind and Bi syndrome.2.2Syndrome elements of disease location distribution of type2DACISyndrome elements of disease location which closely tied to type2 DACI are:mind or brain,lung,liver,kidney,channel.Mild typing aremainly composed by liver and channel. Moderate typing are mainlycomposed by liver,channel and mind/brain constituent ratio rise. Severetyping are mainly composed by liver,channel and mind/brain.2.3The relation between typing of type2DACI and syndrome elementsThe emergence rate of channel is always high,between67.31%and100.00%, comparison between mild risk and severe risk, P<0.05, has asignificant difference. comparison between moderate risk and severe riskP<0.05, has a significant difference.The channel Shows ascendant trend.The emergence rate of the mind were between5.77%and50.00%,comparison between mild risk and severe risk, P<0.05, comparisonbetween moderate risk and severe risk P<0.05, both has a significantdifference.The emergence rate of internal wind were in the range of36.54-and80.00%, comparison between mild risk and severe risk, P<0.05,comparison between mild risk and moderate risk P<0.05,both has asignificant difference. There is a rising trend from mild to severe,thehighest emergence rate is severe. The emergence rate of blood stasiswere in the range of7.69%-40.00%, comparison between mild risk andsevere risk P<0.05, comparison between moderate risk and severe riskP<0.05, both has a significant difference. The emergence rate of Bisyndrome were in the range of1.92%-60%, comparison between mildrisk and severe risk P<0.05, comparison between moderate risk andsevere risk P<0.05, both has a significant difference.2.4The combination of TCM syndrome elements2.4.1The combination of TCM syndrome elements of disease natureIn the combination of mild typing: single syndrome elementaccount for15.38%, two syndrome elements account for38.46%, threesyndrome elements account for19.23%, four syndrome elementsaccount for17.31%, five syndrome elements account for7.69%, sixsyndrome elements account for1.92% In the combination of moderate typing: single syndrome elementaccount for3.85%, two syndrome elements account for38.46%, threesyndrome elements account for23.08%, four syndrome elementsaccount for11.54%, five syndrome elements account for7.69%, sixsyndrome elements account for3.85%, seven syndrome elementsaccount for7.69%.In the combination of moderate typing: two syndrome elementsaccount for10.00%, three syndrome elements account for20.00%, foursyndrome elements account for20.00%, five syndrome elementsaccount for30.00%, six syndrome elements account for20.00%.2.4.2The combination of TCM syndrome elements of disease locationIn the combination of mild typing: single syndrome elementaccount for34.62%, two syndrome elements account for40.38%, threesyndrome elements account for19.23%, four syndrome elementsaccount for3.85%。In the combination of moderate typing: single syndrome elementaccount for26.92%, two syndrome elements account for61.54%, threesyndrome elements account for7.69%, five syndrome elements accountfor3.85%.In the combination of moderate typing: two syndrome elementsaccount for50.00%, three syndrome elements account for20.00%, foursyndrome elements account for20.00%, five syndrome elementsaccount for10.00%.Conclusions:The emergence rate of channel and liver had been ata much high level in the disease location of Type2DACI, They had arisk trend from mild type to severe type. The emergence rate of phlegminternal wind and Yin deficiency were in a high level in the syndromeelements of Type2DACI. Combine disease location with syndromeelements, there were Yin deficiency of liver causing internal wind,phlegm block channel. Comparison emergence rate of channel andinternal wind between severe type moderate type and mild type, both has a significant difference. Comparison emergence rate of blood stasis Bisyndrome mind between severe type and moderate type mild type, bothhas a significant difference. In short, typing of type2DACI has somerelationship with TCM syndrome. It can provide reference for TCMtreatment of type2DACI. |
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