Application Of Macrocyclic Complex Catalyzed Belousov-Zhabotinskii Oscillating Chemical Reaction In The Determination

Chemical oscillation is a nonlinear non-equilibrium phenomenon, which is found in the nature. The special behaviors of oscillating chemical reaction, especially tetraazamacrocycle complexes catalyzed oscillating chemical reactions, have become of great interest in many science workers in the world. These tetraazamacrocyclic complexes have a similar structure to some enzymes in life system, and these enzymes play a important role in the process of life. Hence, studiing oscillating reactions catalyzed by these complexes, will help us to simulate oscillation phenomena in plants and animals. A novel B-Z oscillating system involving a macrocyclic copper(Ⅱ) complex [CuL](ClO4)2as catalyst and malic acid as the substrate was applied to determine paracetamol, gentisic acid and8-Quinolinol. The ligand L in the complex is5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradeca-4,11-dine. The dissertation contains the following works:1. The Summary of chemical oscillating reactionThis chapter discusses the development history of chemical oscillation, and it introduces the basic conditions for chemical oscillating reaction and several usual oscillating chemical reactions, and the mechanisms of classical. Novel B-Z oscillating reactions were described in details. At the last, the application of oscillating chemical reactions and the development prospects are also reviewed.2. Chemical synthesis of macrocyclic complex [CuL](ClO4)2and the determination of paracetamolFirstly, The tetraazamacrocyclic complex (catalyst,[CuL](ClO4)2) was synthesized according to literature and was identified by I.R. spectrum and elemental analyses. Then, establish the stable novel B-Z oscillating system, which involves a macrocyclic copper(Ⅱ) complex [CuL](ClO4)2as catalyst and malic acid as the substrate. By perturbation mount of paracetamol on the B-Z system, there is a linear relationship between the changes in the oscillation amplitude and the logarithm of paracetamol concentration in the range5×10-7to2×10-4mol/L, with a correlation coefficient of0.99743. The effects of influential variables, such as the concentration of reaction components, temperature and on the determinations were studied. The probable mechanism involving the perturbation of paracetamol on the oscillating chemical system were also discussed.3. Determination of gentisic acid and study of its mechanismA new method for the determination of the gentisic acid based on the perturbation caused by different amounts of gentisic acid on the B-Z oscillating system (NaBrO3-H2SO4-malicacid-[CuL](ClO4)2). There is a linear relationship between the changes in the oscillation amplitude and the logarithm of gentisic acid concentration in the range1.25×10-6to1×10-4mol/L, with a correlation coefficient of0.99821. Effects of concentration of reaction components and the probable mechanism involving the perturbation of gentisic acid on the oscillating chemical system were also discussed.4. Determination of8-Quinolinol on [CuL](ClO4)2-catalyzed oscillating reactionA new analytical method for the determination of8-Quinolinol by the perturbation caused by different amounts of8-Quinolinol on the oscillating chemical system, involving the [CuL](ClO4)2-catalyzed oscillating system, is established. The method relies on the linear relationship between the changes in the amplitude and the logarithm of the concentration of8-Quinolinol in the range2.5×10-6to2.5×10-4M, with a correlation coefficient of0.9976. The probable mechanism involving the perturbation of8-Quinolinol on the oscillating chemical system was also discussed...