Synthesis And Application Of Some Novel Schiff Bases Containing A Ferrocenyl Group And Its Complexes

Generally, ferrocene and its derivatives usually show special properties due to their unique structures. Such as the hydrophobic, oxidationabillity, stability and so on. There has been growing interest in their application in medicine, molecular recognition, electrochemical, combustion-supporting agent and biological sensors et. al. Recently, Schiff bases containing a ferrocenyl group have been studied widely, their transition metal complexes can be used as antimicrobial, anticancer drugs with certain physiological activity. Recent research focuses on their synthesis, characterization and bioactivity, there are fewer reports on the other applications such as electroactive sensors.In addition, metallic complexes containing a ferrocenyl group have been used as neutral carriers for ISEs according to the literatures. Because of the unique stereo structures, they have always been anion recognition carriers for the analytical determination of some anions, such as iodide, sulfate, nitrate et. al. The electrodes based on the above carriers always show excellent selective porperties with wide linear response range.In this paper, ten Schiff bases and several organometallic complexes have been synthesized, their structures have been characterized by elemental analysis, ir spectroscope,1H NMR spectroscope. The main works of this paper are as follows:1. The novel Schiff base was synthesized by the condensation reaction of1-ferrocenyl-1,3-dioxobutane with3-Mercapto-2-butanon respectively. Its structure was characterized by elemental analysis, ir spectroscope,1H NMR spectroscope.2. Modifying the golden electrodes by the Schiff base, the impact made by the hydrophobic and hydrophilic anion on the transfer of electrodes on the surface of ferrocene and golden electrodes as well as its influence on the oxidization of ascorbic acid were discussed. Meanwhile, the electrochemistry property of the Schiff base was studied.3. The corresponding Schiff base was synthesized by the condensation reaction of ferrocenyl phenylamine with4-Bromothiophene-2-carbaldenhyde,5-Bromothiophene-2-carbaldenhyde,5-Bromopyridine-2-carbaldehyde and5-Bromosalicyladehyde. Using the corresponding schiff bases as the ligand, the corresponding complexes of Cu(Ⅱ), Co(Ⅱ) and Zn(Ⅱ) were synthesized and their structures were represented.4. Another three new Schiff bases were synthesized by the condensation reaction of ethylenediamine with5-bromosalicyladehyde,5-chloro-2-hydroxybenzaldehyde and2-hydroxy-5-nitrobenzaldehyde respectively. Based on the compound as the ligand, nine complexes of Cu(Ⅱ), Co(Ⅱ) and Mn(Ⅱ) were synthesized respectively, their structures were characterized by elemental analysis, ir spectroscope,1H NMR spectroscope. Using the prepared Schiff base compound complexes of Cu(Ⅱ), Co(Ⅱ) and Mn(Ⅱ) as the carriers, the anion responding behavior was investigated, and its influence on the responding properties of the electrodes by different structures was observed.