Synthesis And Analytical Applications Of Heterocyclic Pentcoordinated Organotin Complexes

Organotin(IV) complexes of Schiff bases have extentively bioactivity activities, especially anti–tumour activity, so its have recently increased attention. Organotin(IV) complexes of Schiff bases may use as neutral carriers in the anion–selective electrodes because of unique stereo structure and Louis acid. Design and synthesis of high–selectivity anti–Hofmeister pattern anion selective electrodes has been one of the important area in the research of chemical sensors. Compared with the classic solvent polymer membrane ion–selective electrodes based on ion–exchange reagents, the electrodes based on organometallic compounds and metal complexes always show higher selectivity and sensitivity towards anions. In this paper, three series of heterocyclic pentcoordinated organotin(Ⅳ) Schiff base complexes have been synthesized, its anion recognition properties was also investigated.1. Eight hydrazone Schiff bases have been synthesized by the reaction of salicylaldehyde, o–vanillin, 2-hydroxy-1-naphthaldehyde with nicotinic or isonicotinoyl hydrazide in anhydrous ethanol respectively; Three thiosemicarbazone Schiff bases have been synthesized by the reaction of salicylaldehyde, o–vanillin, o–hydroxyacetophenon with thiosemicarbazide in hydrous-ethanol respectively. Their structures were characterized.2. Dibenzyltin, diphenyltin dichloride and di–n–butyltin dichloride have been synthesized by the literature method. Twelve novel heterocyclic pentcoordinate organotin(Ⅳ) Schiff base complexes have been synthesized by the reaction of dibenzyltin dichloride, diphenyltin dichloride and di–n–butyltin dichloride with the nicotinic hydrazone Schiff bases in anhydrous methanol. Their structures were characterized.3. Dibenzyltin, diphenyltin dichloride and di–n–butyltin dichloride have been synthesized by the literature method. Twelve novel heterocyclic pentcoordinate organotin(Ⅳ) Schiff base complexes have been synthesized by the reaction of dibenzyltin dichloride, diphenyltin dichloride and di–n–butyltin dichloride with the isonicotinoyl hydrazone Schiff bases in anhydrous methanol. Their structures were characterized.4. Six novel heterocyclic pentcoordinate organotin(Ⅳ) Schiff base complexes...