Metal-free Construction Of Benzo[4,5]Imidazo[2,1-a]Isoindole And1,2-dialkyl-2,3-dihydrobenzimidazoles In The Presence Of Acid

A facile and environmental method was introduced in this article, across the coupling of dialdehyde and o-diaminobenzene, a series of Benzo[4,5]imidazo[2,1-a]isoindole andl,2-dialkyl-2,3-dihydrobenzimidazoles were constructed and the yields were high. Because of the skeleton of azoles in the compounds, the compounds have widely used in the field of xerography, organic electronics and so on. Moreover, the azoles, which contain C=N bond have received epochal attention because of azoles’potential application as ligands. During the past decades, several transition-metal-catalyzed methods for synthesis of a variety of N-heterocyclic compounds have been emerged. However, their corresponding catalytic systems have some drawbacks:they were complicated, the crude materials and catalysts were obtained difficultly. In this paper, I have a summary on such reactions and synthetic methods, and describe my work specifically at the same time.The first chapter is to introduce the synthesis of azoles, which has the main idea of the synthetic methods on1,2,3-azoles and imidazole in recent years.The second chapter is to introduce the schiff’s base compounds. Across the coupling of aldehyde and amine, kinds of benzimidazole and imidazole derivatives were produced.The third chapter is to introduce my work about the reaction of dialdehyde and o-diaminobenzene, which is the basic of this article.The forth chapter is to introduce the bridge ring compounds simply, which bases on the uncompleted article. We employed iron as catalyst, chalcone as the substrate, to synthesis a series of goal compounds.