Evaluation Of Left Ventricular Longitudinal View Myocardial Function Before And After Coronary Artery Bypass Graft In Patients With Coronary Artery Disease By Two Dimensional Strain Echocardiography

Background In recent years, with coronary artery diseases incidence increased, morepatients accepted coronary artery bypass graft (CABG). Myocardial arteries were remodeled byCABG, and to improve myocardial blood supply. CABG had been acknowledged as the effectivemethod in the field of surgery to the patients with coronary artery diseases (CAD). Recently,Whether the changes of left ventricular myocardial function after and before CABG wereaccurately evaluated by two-dimensional strain echocardiography (2DS), it was the focal point athome and abraod. The detection of clinic effective to patients with CABG also got muchattention.Speckle tracking echocardiography (STI) was the foundation of2DS.2DS hadadvantages at evaluating myocardial function as a new technology. Because myocardial functionrelated to left ventricular motion, the changes of S, SRs in different regional left ventricular wasdetected by2DS. Useful clinic evidences were gotten by2DS.Objective To evaluate treatment effect in clinic of coronary artery bypass graft (CABG)in patients with coronary artery diseases (CAD) by two dimensional strain echocardiography(2DS).Methods The values of systolic strain (S) and strain rate (SRs) at9segments suppliedby the left anterior descending of coronary were measured in study group that consisted of22patients with CAD at1week before surgery and1week,1month,3months after CABG. Thevalues of S, SRs at the same segments in30normal subjects were measured with the sametechnique, and were compared with that in patients with CAD at1week before surgery. Then thepeaks of S, SRs in these segments at1week before surgery and at1week,1month,3monthsafter CABG in patients with CAD were compared and the changes were analyzed.Results In the normal group, the curves of S, SRs displayed a wide and negative peakand were homogeneous in every segments at all cardiac cycle. The values of S, SRs peakdecreased, and the homogeneity disappeared in study group compared with that in normalsubjects (P0.05).1month after CABG, the peak of S, SRs increased in varying degreescompared with before surgery (P0.05). Changes were obviously at3months after CABG, thecurves of S, SRs in all segments were regular, peaks of S, SRs approach the level of normal segments.Conclusion2DS can evaluate the changes of S, SRs non-invasively and quantitativelyat different time points after CABG in patients with CAD, and assess the myocardial function.