Clinical Alue Of Diffusion-weighted With Background Suppression In Lymph Node Diseases Of Gastric Cancer

Objective This study was to investigate the value of diffusion weightedwhole body imaging with background suppression（DWIBS）in differentiationbetween benign,malignant lymph nodes and lymphoma in abdominal lymphnodes （celiac and inguinal lymph nodes）.Methods DWIBS（b＝800）sequence records of225abdominal lymphnodes confirmed by operation and pathology were studied，including135intraperitoneal metastatic lymph nodes,90benign lesions.The apparentdiffusion coefficients （ADC） of malignant lesions benign lesions andlymphomas were compared. The diagnosis threshold between malignant andbenign lesions was decided according to ROC curve．Results1.statistical analysis shows two methods to judge the uniformityof metastatic lymph nodes between the analytical result from the group（diameter≥10mm） and pathological findings （Kappa=2.04, Pï¹¥0.05）. Thesensitivity of DWIBS to diagnose the lymph nodes metastasis of gastric canceris77.8%, and the specificity is83.3%.The conclusion of this study supportsthat it can be a standard for DWIBS to decide lymph node metastasis that thelength of diameter is or over10mm.2.The mean ADC value of benign lymphnodes,metastatic lymph nodes and lymphomas were （1.410±0.221）×10－3mm²/s，（0.887±0.186）×10^－3mm²/s. There were significant differences amongthese ADC values（P＜0.05）．When an ADC value was less than1.01×10－3mm²/s， it was used as the threshold for metastatic nodes, where sensitivity of 85ï¼…and specificity of82%were available and the diagnostic value was verygood （P＜0.05）．Conclusion DWIBS may be applied to detect celiac lymph nodediseases．ADC value and diameter may help to differentiate between benignand malignant abdominal lymph node lesions, and offer the valuablereference for choosing proper preclinical surgical technique and assessing theprognosis.