| Objective:To investigate the effect of early intervention on the prevention and control of the high-risk infant abnormal development of nervous system, to analyze the relevant factors of effects, and to provide a scientific basis for formulate the related management strategies of high-risk infant.Methods:The object of study was136cases of high-risk infant and15cases of normal infants. Establish health records,help the parents to implement a comprehensive early intervention, acess them on a regular basis and record the tracking information for those136cases of high-risk children and15cases of normal newborns.And then carry on the nervous system development assessment relying on Gesell development schedule and compare the intervention effect.Results:In the follow-up process, there were32cases lost, finally collected104caseswhose information complete. Thro ugh implement comprehensive early intervention on the high-risk infants for six months,showed that:1.The developmental quotient(DQ) of high-risk infant aged1month,3months,6months ascended.The result by analysis of variance (ANOVA) showed that:The DQ value of language between3months and6months had no significant differences(P>0.05). Other pairwise comparison had no significant differences (P<0.05or P<0.01,);DQ value between high-risk infant and normal infant at6months of age had no significant difference (P>0.05).2.The higher score of implementation of the interventions, the higher the DQ value (P<0.05).3.The increase of the number of times of follow-up, the better compliance (P<0.05).4.The factors influencing the DQ value of the rough action of high-risk infant had intracranial hemorrhage,mather used drug during pregnancy, prenatal education, leg cramped during pregnancy, dependents within a month. The factors influencing the DQ value of elaborate activity of high-risk infant have low birth weight, hypoxic-ischemic encephalopathy(HIE),respiratory distress syndrome(RDS), prenatal education. The factors influencing the DQ value of object ability have intracranial hemorrhage, RDS, prenatal education and father’s occupation. The factors influencing the DQ value of language ability have prenatal education and the father’s smoking capacity, the demographic of living together. The factors influencing the DQ value of personal-social behaviour have intracranial hemorrhage, prenatal education, dependents within a month (P<0.05)Conclusions:1.System management and implementing comprehensive early intervention of104high-risk infants can promote the development of nervous system of them; and the effect according to the better compliance.2.The main factors affect early intervention of high-risk infant are the sex,high risk factors, age of mother, medication and prenatal history of pregnancy, smoking history of father,dependents, living environment. |